Association between mortality and cognitive change over 7 years in a large representative sample of UK residents.
Objective: To examine the association between change in reaction time and cognitive performance over 7 years and the risk of death from all causes and some specific causes after controlling for known risk factors.Methods: The sample comprised members of the Health and Lifestyle Survey (HALS) of comm...
| Publicado en: | Psychosomatic Medicine Vol. 69; no. 7; pp. 640 - 651 |
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| Autores principales: | , , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
2007 Sep
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105830778&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105830778 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00333174 2C8 jtl: Psychosomatic Medicine issn: 00333174 maglogo: N pubinfo: dt: 2007 Sep vid: 69 iid: 7 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 105830778 105830778 NLM17846257 2009698121 10.1097/psy.0b013e31814c3e7c NLM17846257 105830778 ppf: 640 ppct: 11 formats: tig: atl: Association between mortality and cognitive change over 7 years in a large representative sample of UK residents. aug: au: Shipley BA Der G Taylor MD Deary IJ Shipley, Beverly A Der, Geoff Taylor, Michelle D Deary, Ian J affil: Psychology, School of Philosophy, Psychology and Language Sciences, University of Edinburgh, 7, George Square, Edinburgh, Scotland, UK sug: subj: Cognition Disorders Mortality Adolescence Adult Aged Aged, 80 and Over Cause of Death Female Great Britain Male Middle Age Prospective Studies Reaction Time Risk Factors Surveys Human Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: Objective: To examine the association between change in reaction time and cognitive performance over 7 years and the risk of death from all causes and some specific causes after controlling for known risk factors.Methods: The sample comprised members of the Health and Lifestyle Survey (HALS) of community-dwelling adults in England, Scotland, and Wales. Baseline testing (HALS1), involving 9003 people, took place in 1985 and 1986. Sociodemographic, lifestyle, health, and physiological information was collected. Cognitive functioning was measured using tests of simple and choice reaction time, a short memory test, and a test of visual-spatial reasoning. Follow-up testing (HALS2) took place in 1991 and 1992, when 5352 members of the study were administered the same questionnaires, physiological examinations, and cognitive tests. The sample has been followed for mortality up to June 2005.Results: After controlling for age, gender, and the relevant baseline cognitive test scores, greater declines between HALS1 and HALS2 on simple reaction time mean and variability, choice reaction time mean and variability, memory and visual-spatial reasoning were associated with significantly increased risks of death from all causes, all cardiovascular diseases (CVDs), coronary heart disease (CHD), stroke, and respiratory disease. These associations were only slightly attenuated after adjusting for occupational social class, educational, smoking, alcohol consumption, physical activity, body mass index, blood pressure, and lung function.Conclusions: Decline in performance of reaction times and simple cognitive tasks across a 7-year period was associated with an increased risk of death from all causes, all CVDs, CHD, stroke, and respiratory disease up to 13 years later, even after adjustment for known risk factors. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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