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Cryptococcus neoformans Abscess and Osteomyelitis in an Immunocompetent Patient with Tuberculous Lymphadenitis.

Infection with Cryptococcus neoformans usually occurs in immunocompromised hosts and may occur in immunocompetent patients. Of all cryptococcal infections, 10-40% of patients have no apparent immune deficiency. Disseminated disease may occur in up to 62% of HIV-seronegative patients with cryptococco...

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Published in:Infection Vol. 35; no. 5; pp. 377 - 383
Main Authors: Al-Tawfiq JA, Ghandour J
Format: case study Journal Article
Published: Springer Nature Oct2007
Online Access:View this record in EBSCOhost
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      dt: Oct2007
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s15010-007-6109-9
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        atl: Cryptococcus neoformans Abscess and Osteomyelitis in an Immunocompetent Patient with Tuberculous Lymphadenitis.
      aug:
        au:
          Al-Tawfiq JA
          Ghandour J
        affil: Internal Medicine Services Division, Dhahran Health Center, Saudi Aramco Medical Services Organization, P. O. Box 76, Room A-420, Building 61, Saudi Aramco, Dhahran, 31311, Saudi Arabia, jaffar.tawfiq@aramco.com.
      sug:
        subj:
          Abscess Microbiology
          Cryptococcosis Complications
          Cryptococcosis Microbiology
          Osteomyelitis Microbiology
          Tuberculosis Complications
          Abscess Drug Therapy
          Adult
          Antifungal Agents Therapeutic Use
          Antitubercular Agents Therapeutic Use
          Cryptococcosis Drug Therapy
          Cryptococcus
          Female
          Fluconazole Therapeutic Use
          Osteomyelitis Drug Therapy
          Spine Pathology
          Adult: 19-44 years
          Female
      ab: Infection with Cryptococcus neoformans usually occurs in immunocompromised hosts and may occur in immunocompetent patients. Of all cryptococcal infections, 10-40% of patients have no apparent immune deficiency. Disseminated disease may occur in up to 62% of HIV-seronegative patients with cryptococcosis; however, cryptococcal osteomyelitis is rare. Here, we report an immunocompetent patient with cryptococcal vertebral osteomyelitis and concomitant tuberculous lymphadenitis. The patient received 12 weeks of fluconazole and a 1-year course of anti-tuberculous agents, with complete recovery.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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