Degeneration speed of corticospinal tract in patients with cerebral infarct.

Objectives: Diffusion tensor image tractography (DTT) could be useful for exploring the state of the corticospinal tract (CST) at the level of the subcortical white matter. The purpose of this study was to demonstrate the speed of degeneration of the CST in patients with cerebral infarct, using DTT....

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Publicado en:NeuroRehabilitation Vol. 22; no. 4; pp. 273 - 278
Autores principales: Kim DG, Ahn YH, Byun WM, Kim TG, Yang DS, Ahn SH, Cho YW, Jang SH
Formato: case study research Journal Article
Publicado: Sage Publications Inc. 2007
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Sage Publications Inc.
      place: Thousand Oaks, California
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        atl: Degeneration speed of corticospinal tract in patients with cerebral infarct.
      aug:
        au:
          Kim DG
          Ahn YH
          Byun WM
          Kim TG
          Yang DS
          Ahn SH
          Cho YW
          Jang SH
        affil: Department of Physical Medicine & Rehabilitation, Yeungnam University College of Medicine, Taegu, Republic of Korea.
      sug:
        subj:
          Infarction Pathology
          Neural Pathways Pathology
          Adult
          Infarction Complications
          Infarction Physiopathology
          Magnetic Resonance Imaging
          Male
          Middle Age
          Time Factors
          Human
          Adult: 19-44 years
          Middle Aged: 45-64 years
          Male
      ab: Objectives: Diffusion tensor image tractography (DTT) could be useful for exploring the state of the corticospinal tract (CST) at the level of the subcortical white matter. The purpose of this study was to demonstrate the speed of degeneration of the CST in patients with cerebral infarct, using DTT.Design: Two patients with middle cerebral artery territory infarct were recruited for this study. DTT was performed 5 times with an interval of 7 days, starting at 2 days after onset, using a 1.5-T system with a synergy-L Sensitivity Encoding head coil. The termination criteria used were fractional anisotrophy < 0.3, 0.2, 0.1, respectively, and an angle change > 45 degrees . Results: Detection of CST degeneration began at the 9 day DTT in both patients. The most rapid CST degeneration was noted for 7 days at 16 days from onset. We did not detect any tract in the affected hemisphere of both patients at the 23-day DTT. Conclusions: We demonstrated that CST degeneration begins before 9 days from onset and progresses rapidly in patients with middle cerebral artery territory infarct. It seems that the CST degeneration began earlier than expected.
      pubtype: Academic Journal
      doctype:
        case study
        research
        Journal Article
      ougenre: Article
    language: English
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