Population pharmacokinetic investigation of low-dose methotrexate in rheumatoid arthritics Japanese patients.
OBJECTIVE: To estimate the population pharmacokinetics of low-dose methotrexate (MTX) in Japanese patients using nonmem, a computer program designed for analysing drug pharmacokinetics in study populations through pooling of data. METHOD: A total of 153 serum concentration measurements obtained from...
| Publicado en: | Journal of Clinical Pharmacy & Therapeutics Vol. 32; no. 6; pp. 573 - 579 |
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| Autores principales: | , , , |
| Formato: | research Journal Article |
| Publicado: |
Wiley-Blackwell
Dec2007
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| Acceso en línea: | Ver este registro en EBSCOhost |