Determining acute health hazard ratings in the absence of applicable toxicological data.
Health, safety, and emergency planning professionals have a responsibility to identify acute hazards associated with chemicals and to find a way to transmit that information to chemical users, emergency responders, and others. Various organizations such as the Department of Energy are considering ac...
| Publicado en: | Journal of Occupational & Environmental Hygiene Vol. 4; no. 11; pp. 841 - 848 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Nov2007
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105845562&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105845562 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15459624 V1L jtl: Journal of Occupational & Environmental Hygiene issn: 15459624 maglogo: Y pubinfo: dt: Nov2007 vid: 4 iid: 11 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 105845562 105845562 2009676569 NLM17885911 105845562 ppf: 841 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Determining acute health hazard ratings in the absence of applicable toxicological data. aug: au: Simmons F Quigley D Freshwater D Whyte H Boada-Clista L Laul JC sug: subj: Disaster Planning Standards Emergencies Environmental Exposure Analysis Environmental Health Hazardous Materials Analysis Acute Disease Animals Disaster Planning Methods Environmental Exposure Adverse Effects Hazardous Materials Hazardous Materials Classification Risk Assessment Safety Toxicity Tests United States United States Environmental Protection Agency ab: Health, safety, and emergency planning professionals have a responsibility to identify acute hazards associated with chemicals and to find a way to transmit that information to chemical users, emergency responders, and others. Various organizations such as the Department of Energy are considering acute health hazard ratings as triggers that would mandate various activities. A paradigm shift away from a 'lists' based approach to determining whether a chemical is sufficiently hazardous to require further analysis for emergency planning purposes is under way. Various toxicological data sources and approaches in use to develop an acute health hazard rating are discussed. Methods of extrapolating data from published and unpublished supporting documentation to develop an acute health hazard rating in the absence of toxicological data by animal species, chemical structure similarities, MSDS estimated values, and data mining are discussed. The process described analyzes applicable data and allows the analyst to determine reasonable health hazard rating numbers for chemicals without published hazard ratings and for mixtures of chemicals. The level and amount of resources available will determine which methods will be used in the process. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|