Comprehensive analysis of BCR-ABL transcript types in Korean CML patients using a newly developed multiplex RT-PCR.

Diagnosis of chronic myeloid leukemia (CML) is based on the detection of BCR-ABL gene or Philadelphia chromosome (Ph chromosome), and fusion proteins with different sizes are encoded depending on the breakpoint in the BCR gene. In general, 3 breakpoint cluster regions in the BCR gene have been descr...

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Publicado en:Translational Research: The Journal of Laboratory & Clinical Medicine Vol. 148; no. 5; pp. 249 - 257
Autores principales: Goh HG, Hwang JY, Kim SH, Lee YH, Kim YL, Kim DW
Formato: research Journal Article
Publicado: Elsevier B.V. Nov2006
Acceso en línea:Ver este registro en EBSCOhost