Pyoderma gangrenosum: an update.

Pyoderma gangrenosum (PG) can be differentiated into classic and atypical forms. The classic form is characterized by ulcers and the atypical form by deep erosions with bullous blue-gray margins. Pathergy, the development of cutaneous lesions at sites of trauma, is a common feature of both forms of...

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Detalles Bibliográficos
Publicado en:Rheumatic Disease Clinics of North America Vol. 33; no. 4; pp. 787 - 804
Autores principales: Callen JP, Jackson JM
Formato: Journal Article
Publicado: W B Saunders 2007 Nov
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Pyoderma gangrenosum (PG) can be differentiated into classic and atypical forms. The classic form is characterized by ulcers and the atypical form by deep erosions with bullous blue-gray margins. Pathergy, the development of cutaneous lesions at sites of trauma, is a common feature of both forms of PG. Approximately 50% of patients who have PG have underlying systemic diseases, most commonly inflammatory bowel disease, myeloproliferative disorders, and various forms of inflammatory arthritis. The diagnosis of PG is one of exclusion. The management of this disorder begins with treatment of any underlying disease and local or systemic glucocorticoids or immunomodulating therapies.Copyright © 2007 by Elsevier Inc.