Children's and parents' perspectives on open-label use of placebos in the treatment of ADHD.
Background The purpose of this study was to examine the efficacy and acceptability of an open-label conditioned placebo dose reduction (CPDR) treatment in 70 children with attention deficit hyperactivity disorder (ADHD). This paper focuses on the qualitative data from the study. Methods Following a...
| Publicado en: | Child: Care, Health & Development Vol. 34; no. 1; pp. 111 - 121 |
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| Autores principales: | , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Wiley-Blackwell
Jan2008
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105877168&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105877168 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03051862 6NX jtl: Child: Care, Health & Development issn: 03051862 maglogo: Y pubinfo: dt: Jan2008 vid: 34 iid: 1 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 105877168 105877168 2009744578 10.1111/j.1365-2214.2007.00797.x NLM18171452 105877168 ppf: 111 ppct: 10 formats: fmt: @attributes: type: P tig: atl: Children's and parents' perspectives on open-label use of placebos in the treatment of ADHD. aug: au: Sandler A Glesne C Geller G affil: Olson Huff Center, Mission Children's Hospital, Asheville, NC, USA sug: subj: Attention Deficit Hyperactivity Disorder Drug Therapy Central Nervous System Stimulants Administration and Dosage Clinical Trials Evaluation Parental Attitudes Patient Attitudes Placebos Administration and Dosage Adolescence Child North Carolina Placebo Effect Placebos Ethical Issues Qualitative Studies Structured Interview Thematic Analysis Human Adolescent: 13-18 years Child: 6-12 years ab: Background The purpose of this study was to examine the efficacy and acceptability of an open-label conditioned placebo dose reduction (CPDR) treatment in 70 children with attention deficit hyperactivity disorder (ADHD). This paper focuses on the qualitative data from the study. Methods Following a double-blind, crossover dose finding procedure to determine each subject's optimal dose of stimulant medication, subjects were randomized to the CPDR treatment or one of two control groups. Outcome measures included parent and teacher ratings of ADHD behaviours and stimulant side effects. Qualitative assessments were based on open-ended interviews of children and parents. Positive responders to CPDR and controls were followed for 3 months to assess persistence of treatment benefits. Results Children randomized to CPDR showed an excellent treatment response, well maintained over time. Parents and children were generally accepting of the treatment. Most parents reported treatment benefits and 80% of the children found the placebo to be useful. Full disclosure of the placebo to parents and children did not appear to negate the placebo's effectiveness. Participation effects and changes in caregiver behaviour may have contributed to positive treatment outcomes. Conclusions Open-label use of placebos as part of CPDR treatment may represent an innovative, ethical way of harnessing the power of placebos in clinical therapeutics. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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