Bottlenecks in development of retinal therapeutic post-transcriptional gene silencing agents.

Development of post-transcriptional gene silencing (PTGS) agents for therapeutic purposes is an immense challenge in modern biology. Established technologies used to knockdown a specific target RNA and its cognate protein: antisense, ribozyme, RNAi, all conditionally depend upon an initial, critical...

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Detalles Bibliográficos

Publicado en:	Vision Research Vol. 48; no. 3; pp. 453 - 470
Autores principales:	Sullivan JM, Yau EH, Taggart RT, Butler MC, Kolniak TA, Sullivan, Jack M, Yau, Edwin H, Taggart, R Thomas, Butler, Mark C, Kolniak, Tiffany A
Formato:	review Journal Article
Publicado:	Pergamon Press - An Imprint of Elsevier Science Feb2008
Acceso en línea:	Ver este registro en EBSCOhost