An efficient analytical method for particle counting in evaluating airborne infectious isolation containment using fluorescent microspheres.

The containment performance of patient isolation enclosures, particularly expedient surge capacity enclosures, must be verified to protect health care providers and staff, other patients, and hospital visitors. Tracer gas methods are often used, but requirements for special equipment and training li...

Full description

Bibliographic Details
Published in:Journal of Occupational & Environmental Hygiene Vol. 5; no. 4; pp. 271 - 278
Main Authors: Johnson DL, Lynch RA
Format: research Journal Article
Published: Taylor & Francis Ltd Apr2008
Online Access:View this record in EBSCOhost
fields @attributes:
  recordID: 1
pdfLink:
plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105900104&site=ehost-live
header:
  @attributes:
    shortDbName: ccm
    uiTerm: 105900104
    longDbName: CINAHL Complete
    uiTag: AN
  controlInfo:
    bkinfo:
    dissinfo:
    jinfo:
      jid:
        15459624
        V1L
      jtl: Journal of Occupational & Environmental Hygiene
      issn: 15459624
      maglogo: Y
    pubinfo:
      dt: Apr2008
      vid: 5
      iid: 4
      pid: 377
      pub: Taylor & Francis Ltd
      place: Philadelphia, Pennsylvania
    artinfo:
      ui:
        105900104
        105900104
        2009878792
        NLM18286424
        105900104
      ppf: 271
      ppct: 7
      formats:
        fmt:
          @attributes:
            type: P
      tig:
        atl: An efficient analytical method for particle counting in evaluating airborne infectious isolation containment using fluorescent microspheres.
      aug:
        au:
          Johnson DL
          Lynch RA
        affil: Department of Occupational and Environmental Health, University of Oklahoma Health Science Center, Oklahoma City, Oklahoma 73126-0901, USA. David-Johnson@ouhsc.edu
      sug:
        subj:
          Air Microbiology
          Air Pollution, Indoor Analysis
          Environmental Monitoring Methods
          Equipment and Supplies
          Latex
          Occupational Exposure Analysis
          Air Pollutants, Occupational Analysis
          Environment, Controlled
          Equipment Safety Methods
          Light
          Occupational Health
          Human
      ab: The containment performance of patient isolation enclosures, particularly expedient surge capacity enclosures, must be verified to protect health care providers and staff, other patients, and hospital visitors. Tracer gas methods are often used, but requirements for special equipment and training limit the technique's utility. A technologically simple yet accurate and precise particle-based technique is needed to measure the low count concentrations of escaping airborne particles that might be present outside an isolation enclosure. Reported here is the performance of such a technique employing micrometer-sized fluorescent polystyrene latex microspheres as a surrogate for pathogenic bioaerosols. Particles are released into the isolation enclosure, air is sampled inside and outside the room to capture airborne particles on 25 mm diameter filters, and the number of particles deposited on a filter is quantified using an optimized random field counting approach. The technique accurately estimates the number of surrogate bioaerosol particles on the filter, allowing calculation of the airborne particle concentrations inside and outside the enclosure, and the containment efficiency. This technique can be employed using generally available equipment and inexpensive supplies and also can minimize the number of particle counts that must be performed. The method is shown to be specific, sensitive, and accurate.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
    refInfo:
    holdings:
      @attributes:
        islocal: N