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Antibiotic prescription and cost patterns in a general intensive care unit.

Antibiotic prescription habits, cost pattern, and the prospective intervention in an Intensive Care Unit were analyzed. Methods: Data on antibiotic utilization and costs were collected prospectively from individual electronic charts from August 2003 to January 2004, and retrospectively from August t...

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Publicado en:Pharmacy Practice (1886-3655) Vol. 5; no. 2; pp. 67 - 74
Autores principales: Krivoy N, El-Ahal WA, Bar-Lavie Y, Haddad S
Formato: research tables/charts Journal Article
Publicado: Centro de Investigaciones y Publicaciones Farmaceuticas S.L. Apr2007
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Antibiotic prescription and cost patterns in a general intensive care unit.
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          Krivoy N
          El-Ahal WA
          Bar-Lavie Y
          Haddad S
        affil: Division of Medicine, Clinical Pharmacology Unit, Rambam Medical Center, Haifa, Israel
      sug:
        subj:
          Antibiotics Economics
          Antibiotics Therapeutic Use
          Prescribing Patterns
          Academic Medical Centers
          Costs and Cost Analysis
          Data Analysis Software
          Female
          Intensive Care Units
          Israel
          Male
          Nonparametric Statistics
          One-Way Analysis of Variance
          Prospective Studies
          Retrospective Design
          Treatment Outcomes
          Human
          Female
          Male
      ab:
        Antibiotic prescription habits, cost pattern, and the prospective intervention in an Intensive Care Unit were analyzed. Methods: Data on antibiotic utilization and costs were collected prospectively from individual electronic charts from August 2003 to January 2004, and retrospectively from August to December 2002. Results: A total of 180 and 107 patients were surveyed in 2002 and 2003. In 2002, Piperacillin-Tazobactam (13.8%) and Imipenem/Cilastin (11.2%) were the most prescribed medications; while, in 2003, Vancomycin (12.6%) and Imipenem/Cilastin (11.3%) were prescribed, respectively. Total defined daily dose (DDD) and Drug Utilization 90% (DU90%) index for 2002 and 2003 were 2031.15 and 2325.90 DDDs (p<0.1) and 1777.57 and 2079.61 DU90%, respectively (p<0.1). The Median Total Cost /100 admission days (CI 95%) were NIS13,310 (11,110;18,420) and NIS13,860 (6,710;18,020) (p=0.66), respectively. Conclusions: Interventional programs should focus on promoting infectious control with rational antibiotic prescription aimed at minimizing the future emergence of bacterial resistance and futile expenses.
        Se analizaron los hábitos de prescripción de antibióticos, el modelo de costes, y las intervenciones prospectivas en una Unidad de Cuidados Intensivos. Métodos: Se recogieron prospectivamente datos sobre utilización y costes de antibióticos de los registros electrónicos individuales desde agosto de 2003 a enero de 2004, y retrospectivamente hasta diciembre 2002. Resultados: Se investigó un total de 180 y 107 pacientes en 2002 y 2003. En 2002, la Piperacilina-Tazobactam (13,8%) y el Imipenem/Cilastina (11,2%) fue los más prescritos, mientras que en 2003, se prescribieron vancomicina (12,%) e Imipenem/Cilastina (11,3%). Las dosis diarias definidas (DDD) totales y el índice utilización90% (DU90%) para 2002 y 2003 fueron 2031,15 y 2325,90 DDD (p<0,1). La mediana de coste total /100 días de internamiento (IC95%) fue 13.310NIS (11.110;18.420) y 13.860NIS (6.710;18.020) (p=0,66), respectivamente. Conclusiones: Los programas de intervención deberían enfocarse en promover el control de las infecciones con una prescripción racional de antibióticos centrada en minimizar las futuras apariciones de resistencia bacteriana y los gastos inútiles.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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