Multilayer radial systolic strain can identify subendocardial ischemia: an experimental tissue Doppler imaging study of the porcine left ventricular wall.
AIMS: This study investigates whether subendocardial ischemia can be detected by measuring multilayer radial systolic strain from epicardial tissue Doppler imaging. METHODS: In 10 anesthetized open-chest pigs an extracorporeal shunt from the proximal brachiocephalic to the left anterior descending c...
| Publicado en: | European Journal of Echocardiography Vol. 8; no. 6; pp. 420 - 431 |
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| Autores principales: | , , , , |
| Formato: | pictorial research tables/charts Journal Article |
| Publicado: |
Oxford University Press / USA
Dec2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105942984&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105942984 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15252167 NYG jtl: European Journal of Echocardiography issn: 15252167 maglogo: N pubinfo: dt: Dec2007 vid: 8 iid: 6 pid: 622 pub: Oxford University Press / USA artinfo: ui: 105942984 2009726424 10.1016/j.euje.2007.03.031 NLM17597008 105942984 ppf: 420 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Multilayer radial systolic strain can identify subendocardial ischemia: an experimental tissue Doppler imaging study of the porcine left ventricular wall. aug: au: Matre K Moen CA Fanneløp T Dahle GO Grong K affil: Institute of Medicine, University of Bergen, Haukeland University Hospital, NO-5021 Bergen, Norway. sug: subj: Heart Ventricle, Left Physiopathology Myocardial Ischemia Ultrasonography Swine Systole Animal Studies Descriptive Statistics Echocardiography Echocardiography, Doppler Endocardium Funding Source Heart Septum Abnormalities Cardiac Surgery One-Way Analysis of Variance Post Hoc Analysis Repeated Measures Shunts, Surgical ab: AIMS: This study investigates whether subendocardial ischemia can be detected by measuring multilayer radial systolic strain from epicardial tissue Doppler imaging. METHODS: In 10 anesthetized open-chest pigs an extracorporeal shunt from the proximal brachiocephalic to the left anterior descending coronary artery was constricted in steps. Color microsphere injections and short axis Tissue Velocity Imaging (TVI) recordings were performed with open shunt, with a non-significant stenosis, and with 2 steps of shunt flow reduction. RESULTS: With open shunt and no transmural flow gradient, there was a gradient of peak ejection strain with high values subendocardially for both 4 and 2 layer measurements. For 2 layer measurement strain was 56.0+/-10.5% subendocardially and 22.0+/-5.2% subepicardially. A non-significant stenosis, not altering transmural flow distribution, reduced strain to 40.3+/-5.4% in the endocardial half-layer. With reduced shunt flow resulting in subendocardial ischemia, peak ejection strain decreased further, primarily in inner wall layers, and postsystolic strain became evident. At severe stenosis (52.4+/-1.8% shunt flow reduction) strain was reduced to 3.8+/-3.6% in the subendocardium and 0.0+/-2.6% in the subepicardium. CONCLUSION: Evaluation of myocardial function with multilayer radial systolic strain has a potential for detecting subendocardial ischemia. pubtype: Academic Journal doctype: pictorial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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