Comparison of the diagnostic results of bronchoalveolar lavage with synchronous transbronchial biopsies.
Objective: Bronchoalveolar lavage performed during bronchoscopic examination is a type of cytologic sampling with great diagnostic significance. Its diagnostic value is enhanced when biopsy is unavailable and bronchoalveolar lavage is the unique sample. Determining the diagnostic accuracy of broncho...
| Publicado en: | Turkiye Klinikleri Journal of Medical Sciences Vol. 27; no. 2; pp. 179 - 184 |
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| Autores principales: | , , , , , , |
| Formato: | abstract pictorial research tables/charts Journal Article |
| Publicado: |
Turkiye Klinikleri
2007 Apr
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105956843&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105956843 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 13000292 1VOP jtl: Turkiye Klinikleri Journal of Medical Sciences issn: 13000292 maglogo: N pubinfo: dt: 2007 Apr vid: 27 iid: 2 pid: 67298 pub: Turkiye Klinikleri artinfo: ui: 105956843 105956843 2009612676 105956843 ppf: 179 ppct: 5 formats: tig: atl: Comparison of the diagnostic results of bronchoalveolar lavage with synchronous transbronchial biopsies. aug: au: Barut F Ozdamar SO Bahadir B Gun BD Bektas S Colak S Kuzey GM sug: subj: Biopsy Methods Bronchial Neoplasms Diagnosis Therapeutic Irrigation Methods False Negative Results False Positive Results Sensitivity and Specificity Human ab: Objective: Bronchoalveolar lavage performed during bronchoscopic examination is a type of cytologic sampling with great diagnostic significance. Its diagnostic value is enhanced when biopsy is unavailable and bronchoalveolar lavage is the unique sample. Determining the diagnostic accuracy of bronchoalveolar lavage by comparing it with the diagnostic yield of synchronous biopsies is an indicator of its effectiveness.Material and Methods: In this study, 435 bronchoalveolar lavage and 273 bronchoscopic biopsy specimens obtained from January 2003 to December 2005 in the Department of Pulmonary Diseases were retrospectively evaluated in the Department of Pathology, Faculty of Medicine, Zonguldak Karaelmas University.Results: Overall, 373 cases (85.8%) were diagnosed as benign and 12 cases (2.8%) were reported as malignant, while 18 cases (4.1%) were suspected to be malignant; the remaining 32 cases (7.3%) were reported as inadequate. The numbers and percentages of benign, malignant, suspected malignant and inadequate diagnoses of the 273 bronchoalveolar lavage cases with synchronous transbronchial biopsies were 229 (83.9%), 12 (4.5%), 16 (5.8%), and 16 (5.8%), respectively. After suspected malignant and inadequate samples were excluded, coomparison of cytologic and histologic diagnoses revealed that the diagnostic accuracy of bronchoalveolar lavage cytology was 79.4% and 91.6% for benign and malignant diagnoses, respectively; the rate of false negativity was 20.5% and false positivity was 8.3%.Conclusion: While sampling errors seemed to be the primary reason for false negative and false positive diagnoses, the rate of false cytologic evaluation was lower. Considering the false negative diagnoses for cases without biopsy specimens, comparison of bronchoalveolar lavage diagnoses with synchronous biopsies may serve as a quality control programme, since this condition may significantly influence the clinical course. pubtype: Academic Journal doctype: abstract pictorial research tables/charts Journal Article ougenre: Article language: Turkish refInfo: holdings: @attributes: islocal: N |
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