Transcript array analysis in rheumatology.
Transcript array analysis is a novel technique that examines the expression of thousands of genes simultaneously. Transcript array analyses are being used to clarify the diagnosis and prognosis of malignancies, and to understand the underlying pathogenesis of complex human disorders such as the rheu...
| Publicado en: | Rheumatic Disease Clinics of North America Vol. 28; no. 1; pp. 151 - 179 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
W B Saunders
2002 Feb
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105977390&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105977390 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 0889857X 4GH jtl: Rheumatic Disease Clinics of North America issn: 0889857X maglogo: N pubinfo: dt: 2002 Feb vid: 28 iid: 1 pid: 1351 pub: W B Saunders place: Philadelphia, Pennsylvania artinfo: ui: 105977390 2009785068 NLM11840695 105977390 ppf: 151 ppct: 28 formats: tig: atl: Transcript array analysis in rheumatology. aug: au: Molitor JA Buckner JH Nepom GT sug: subj: Biochips Rheumatic Diseases Rheumatology Trends Animals Rheumatic Diseases Physiopathology RNA Analysis ab: Transcript array analysis is a novel technique that examines the expression of thousands of genes simultaneously. Transcript array analyses are being used to clarify the diagnosis and prognosis of malignancies, and to understand the underlying pathogenesis of complex human disorders such as the rheumatic diseases. In this review, the authors will outline the use of transcript arrays to simultaneously assess gene activation of hundreds or thousands of genes, and their potential use in understanding and managing rheumatic disorders. The authors focus on the use of transcript arrays to confirm and refine disease diagnoses, to generate new hypotheses regarding pathophysiology of rheumatic diseases, and to the possible profiling of patients with respect to their likely response to therapies.Copyright © 2002 by Elsevier Inc. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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