Neuropsychological Functioning of Siblings of Children with Autism, Siblings of Children with Developmental language Delay, and Siblings of Children with Mental Retardation of Unknown Genetic Etiology.

Neuropsychological functioning of 30 siblings of children with autism (AU-S), 28 siblings of children with mental retardation of (MR-S), and 30 siblings of children with developmental language delay (DLD-S) was compared. Two siblings, both AU-S, received diagnoses of pervasive developmental disorder...

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Published in:Journal of Autism & Developmental Disorders Vol. 37; no. 3; pp. 537 - 553
Main Authors: Pilowsky T, Yirmiya N, Gross-Tsur V, Shalev RS
Format: research Journal Article
Published: Springer Nature Mar2007
Online Access:View this record in EBSCOhost
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      dt: Mar2007
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      pub: Springer Nature
      place: New York, New York
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        atl: Neuropsychological Functioning of Siblings of Children with Autism, Siblings of Children with Developmental language Delay, and Siblings of Children with Mental Retardation of Unknown Genetic Etiology.
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          Pilowsky T
          Yirmiya N
          Gross-Tsur V
          Shalev RS
      sug:
        subj:
          Autism Spectrum Disorder
          Language Disorders
          Intellectual Disability
          Neuropsychological Tests
          Siblings
          Adolescence
          Autism Spectrum Disorder Diagnosis
          Autism Spectrum Disorder Psychosocial Factors
          Child
          Cognition Disorders Diagnosis
          Female
          Intelligence Tests
          Language Disorders Diagnosis
          Language Disorders Psychosocial Factors
          Male
          Intellectual Disability Diagnosis
          Intellectual Disability Psychosocial Factors
          Human
          Adolescent: 13-18 years
          Child: 6-12 years
          Female
          Male
      ab: Neuropsychological functioning of 30 siblings of children with autism (AU-S), 28 siblings of children with mental retardation of (MR-S), and 30 siblings of children with developmental language delay (DLD-S) was compared. Two siblings, both AU-S, received diagnoses of pervasive developmental disorder (PDD). More siblings with cognitive disabilities were found in DLD-S than in AU-S. However, these differences disappeared after excluding diagnosed siblings or after accounting for family membership. In sum, despite the elevated incidence of PDD among AU-S, the neuropsychological functioning of the remaining siblings did not convey specific characteristics related to the genetic risk associated with autism, in contrast to the cognitive functioning of the DLD-S, which did reflect a genetic risk.
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    language: English
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