Night heart rate variability and particulate exposures among boilermaker construction workers.
BACKGROUND: Although studies have documented the association between heart rate variability (HRV) and ambient particulate exposures, the association between HRV, especially at night, and metal-rich, occupational particulate exposures remains unclear. OBJECTIVE: Our goal in this study was to investig...
| Publicado en: | Environmental Health Perspectives Vol. 115; no. 7; pp. 1046 - 1052 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
National Institute of Environmental Health Sciences
Jul2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105983620&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105983620 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00916765 3B5 jtl: Environmental Health Perspectives issn: 00916765 maglogo: N pubinfo: dt: Jul2007 vid: 115 iid: 7 pid: 56539 pub: National Institute of Environmental Health Sciences place: Research Triangle Park, North Carolina artinfo: ui: 105983620 105983620 2009614548 10.1289/ehp.10019 NLM17637921 105983620 ppf: 1046 ppct: 6 formats: fmt: @attributes: type: P tig: atl: Night heart rate variability and particulate exposures among boilermaker construction workers. aug: au: Cavallari JM Eisen EA Chen J Fang SC Dobson CB Schwartz J Christiani DC affil: Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts, USA sug: subj: Circadian Rhythm Heart Rate Occupational Exposure Adult Electrocardiography Male Human Adult: 19-44 years Male ab: BACKGROUND: Although studies have documented the association between heart rate variability (HRV) and ambient particulate exposures, the association between HRV, especially at night, and metal-rich, occupational particulate exposures remains unclear. OBJECTIVE: Our goal in this study was to investigate the association between long-duration HRV, including nighttime HRV, and occupational PM(2.5) exposures. METHODS: We used 24-hr ambulatory electrocardiograms (ECGs) to monitor 36 male boilermaker welders (mean age of 41 years) over a workday and nonworkday. ECGs were analyzed for HRV in the time domain; rMSSD (square root of the mean squared differences of successive intervals), SDNN (SD of normal-to-normal intervals over entire recording), and SDNN(i) (SDNN for all 5-min segments) were summarized over 24-hr, day (0730-2130 hours), and night (0000-0700 hours) periods. PM(2.5) (particulate matter with an aerodynamic diameter </= 2.5 microm) exposures were monitored over the workday, and 8-hr time-weighted average concentrations were calculated. We used linear regression to assess the associations between HRV and workday particulate exposures. Matched measurements from a nonworkday were used to control for individual cardiac risk factors. RESULTS: Mean (+/- SD) PM(2.5) exposure was 0.73 +/- 0.50 mg/m(3) and ranged from 0.04 to 2.70 mg/m(3). We observed a consistent inverse exposure-response relationship, with a decrease in all HRV measures with increased PM(2.5) exposure. However, the decrease was most pronounced at night, where a 1-mg/m(3) increase in PM(2.5) was associated with a change of -8.32 [95% confidence interval (CI), -16.29 to -0.35] msec nighttime rMSSD, -14.77 (95% CI, -31.52 to 1.97) msec nighttime SDNN, and -8.37 (95% CI, -17.93 to 1.20) msec nighttime SDNN(i), after adjusting for nonworking nighttime HRV, age, and smoking. CONCLUSION: Metal-rich particulate exposures were associated with decreased long-duration HRV, especially at night. Further research is needed to elucidate which particulate metal constituent is responsible for decreased HRV. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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