Environmental determinants of infectious disease: a framework for tracking causal links and guiding public health research.
BACKGROUND: Discoveries that emerging and re-emerging pathogens have their origin in environmental change has created an urgent need to understand how these environmental changes impact disease burden. In this article we present a framework that provides a context from which to examine the relations...
| Publicado en: | Environmental Health Perspectives Vol. 115; no. 8; pp. 1216 - 1224 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
National Institute of Environmental Health Sciences
Aug2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105983659&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105983659 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00916765 3B5 jtl: Environmental Health Perspectives issn: 00916765 maglogo: N pubinfo: dt: Aug2007 vid: 115 iid: 8 pid: 56539 pub: National Institute of Environmental Health Sciences place: Research Triangle Park, North Carolina artinfo: ui: 105983659 105983659 2009642346 10.1289/ehp.9806 NLM17687450 105983659 ppf: 1216 ppct: 8 formats: fmt: @attributes: type: P tig: atl: Environmental determinants of infectious disease: a framework for tracking causal links and guiding public health research. aug: au: Eisenberg JNS Desai MA Levy K Bates SJ Liang S Naumoff K Scott JC affil: University of Michigan, School of Public Health, Department of Epidemiology, 611 Church St., Ann Arbor, MI 48104-3028 USA sug: subj: Communicable Diseases Etiology Environment Animals Communicable Diseases Transmission Public Health Research Animal Studies ab: BACKGROUND: Discoveries that emerging and re-emerging pathogens have their origin in environmental change has created an urgent need to understand how these environmental changes impact disease burden. In this article we present a framework that provides a context from which to examine the relationship between environmental changes and disease transmission and a structure from which to unite disparate pieces of information from a variety of disciplines. METHODS: The framework integrates three interrelated characteristics of environment-disease relationships: a) Environmental change manifests in a complex web of ecologic and social factors that may ultimately impact disease; these factors are represented as those more distally related and those more proximally related to disease. b) Transmission dynamics of infectious pathogens mediate the effects that environmental changes have on disease. c) Disease burden is the outcome of the interplay between environmental change and the transmission cycle of a pathogen. RESULTS: To put this framework into operation, we present a matrix formulation as a means to define important elements of this system and to summarize what is known and unknown about the these elements and their relationships. The framework explicitly expresses the problem at a systems level that goes beyond the traditional risk factor analysis used in public health, and the matrix provides a means to explicitly express the coupling of different system components. CONCLUSION: This coupling of environmental and disease transmission processes provides a much-needed construct for furthering our understanding of both specific and general relationships between environmental change and infectious disease. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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