Network model of decreased context utilization in autism spectrum disorder.

Individuals with autism spectrum disorders (ASD) demonstrate impaired utilization of context, which allows for superior performance on the 'false memory' task. We report the application of a simplified parallel distributed processing model of context utilization to the false memory task. For individ...

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Publicado en:Journal of Autism & Developmental Disorders Vol. 37; no. 6; pp. 1040 - 1049
Autores principales: Beversdorf D, Narayanan A, Hillier A, Hughes J
Formato: Journal Article
Publicado: Springer Nature Jul2007
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jul2007
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      pub: Springer Nature
      place: New York, New York
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        10.1007/s10803-006-0242-7
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        atl: Network model of decreased context utilization in autism spectrum disorder.
      aug:
        au:
          Beversdorf D
          Narayanan A
          Hillier A
          Hughes J
        affil: Dept of Neurology, Ohio State University Medical Center, Means Hall 469, 1654 Upham Dr, Columbus, OH 43210; david.beversdorf@osumc.edu
      sug:
        subj:
          Autism Spectrum Disorder Physiopathology
          Language Disorders Physiopathology
          Learning
          Memory
          Neural Networks (Computer)
          Organizations
          Attention
          Auditory Perception Physiology
          Autism Spectrum Disorder Diagnosis
          Autism Spectrum Disorder Psychosocial Factors
          Child
          Concept Formation
          Funding Source
          Hippocampus Physiopathology
          Language Disorders Diagnosis
          Language Disorders Psychosocial Factors
          Semantics
          Child: 6-12 years
      ab: Individuals with autism spectrum disorders (ASD) demonstrate impaired utilization of context, which allows for superior performance on the 'false memory' task. We report the application of a simplified parallel distributed processing model of context utilization to the false memory task. For individuals without ASD, experiments support a model wherein presentation of one word, e.g., ''apple,'' strongly activates the neighboring nodes of closely related words such as ''fruit,'' ''tree,'' whereas in ASD these neighboring nodes are relatively less activated. We demonstrate this model to be consistent with the superior performance on recognition testing on the false memory test, but not on free recall. This may have an anatomic basis in diminished hippocampal neuronal arborization and the abnormal minicolumnar pathology in ASD.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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