Antileishmanial and antifungal activity of plants used in traditional medicine in Brazil.
The antileishmanial and antifungal activity of 24 methanol extracts from 20 plants, all of them used in the Brazilian traditional medicine for the treatment of several infectious and inflammatory disorders, were evaluated against promastigotes forms of two species of Leishmania (L. amazonensis and L...
| Publicado en: | Journal of Ethnopharmacology Vol. 111; no. 2; pp. 396 - 403 |
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| Autores principales: | , , , , , , |
| Formato: | research Journal Article |
| Publicado: |
Elsevier B.V.
May2007
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=105997045&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 105997045 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 03788741 3MS jtl: Journal of Ethnopharmacology issn: 03788741 maglogo: N pubinfo: dt: May2007 vid: 111 iid: 2 pid: 1004 pub: Elsevier B.V. artinfo: ui: 105997045 2009582928 10.1016/j.jep.2006.12.006 NLM17234373 105997045 ppf: 396 ppct: 7 formats: tig: atl: Antileishmanial and antifungal activity of plants used in traditional medicine in Brazil. aug: au: Braga FG Bouzada ML Fabri RL de O Matos M Moreira FO Scio E Coimbra ES sug: subj: Antifungal Agents Pharmacodynamics Antiprotozoal Agents Pharmacodynamics Leishmania Drug Effects Medicine, Traditional Plants, Medicinal Animals Antifungal Agents Antiprotozoal Agents Brazil Candida Albicans Drug Effects Cryptococcus Drug Effects Drug Evaluation Leishmania Classification Microbial Culture and Sensitivity Tests Plant Extracts Pharmacodynamics Plant Extracts Therapeutic Use Plants Animal Studies ab: The antileishmanial and antifungal activity of 24 methanol extracts from 20 plants, all of them used in the Brazilian traditional medicine for the treatment of several infectious and inflammatory disorders, were evaluated against promastigotes forms of two species of Leishmania (L. amazonensis and L. chagasi) and two yeasts (Candida albicans and Cryptococcus neoformans). Among the 20 tested methanolic extracts, those of Vernonia polyanthes was the most active against L. amazonensis (IC(50) of 4mug/ml), those of Ocimum gratissimum exhibited the best activity against L. chagasi (IC(50) of 71mug/ml). Concerning antifungical activity, Schinus terebintifolius, O. gratissimum, Cajanus cajan, and Piper aduncum extracts were the most active against C. albicans (MIC of 1.25mg/ml) whereas Bixa orellana, O. gratissimum and Syzygium cumini exhibited the best activity against C. neoformans (MIC of 0.078mg/ml). pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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