The perfect storm: Torsades de Pointes in a child with leukemia.

Torsades de Pointes (TdP) is a life-threatening ventricular arrhythmia that can be associated with metabolic abnormalities, exposure to arrhythmogenic medications, and congenital long-QT syndrome. This report describes a patient with ALL and multiple complications of therapy who developed TdP. The p...

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Detalles Bibliográficos
Publicado en:Pediatric Blood & Cancer Vol. 49; no. 7; pp. 996 - 1000
Autores principales: Bagatell R, Hainstock M, Lowe MC, Barber BJ, Samson RA
Formato: case study research Journal Article
Publicado: Wiley-Blackwell Dec2007
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:Torsades de Pointes (TdP) is a life-threatening ventricular arrhythmia that can be associated with metabolic abnormalities, exposure to arrhythmogenic medications, and congenital long-QT syndrome. This report describes a patient with ALL and multiple complications of therapy who developed TdP. The patient had no evidence of congenital long-QT syndrome, but a constellation of factors appears to have led to QT prolongation, ventricular ectopy, and TdP. Although the patient suffered cardiac arrest, rapid recognition of TdP and prompt defibrillation resulted in an excellent outcome. Pediatr Blood Cancer 2007;49:996-999. (c) 2005 Wiley-Liss, Inc.