Evaluation of the appropriate use of albumin in adult and pediatric patients.

The appropriateness of albumin use and baseline albumin usage patterns were studied. Institutional practice patterns regarding the use of albumin were compared to criteria established by an independent expert panel. Fifty-three institutions, all of which were members of VHA or the University Health-...

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Publicado en:American Journal of Health-System Pharmacy Vol. 60; no. 13; pp. 1330 - 1331
Autores principales: Tanzi M, Gardner M, Megellas M, Lucio S, Restino M
Formato: research Journal Article
Publicado: Oxford University Press / USA 7/1/2003
Acceso en línea:Ver este registro en EBSCOhost
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      dt: 7/1/2003
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      pub: Oxford University Press / USA
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        atl: Evaluation of the appropriate use of albumin in adult and pediatric patients.
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        au:
          Tanzi M
          Gardner M
          Megellas M
          Lucio S
          Restino M
      sug:
        subj:
          Serum Albumin Therapeutic Use
          Adolescence
          Adult
          Aged
          Aged, 80 and Over
          Child
          Child, Preschool
          Drug Utilization
          Female
          Guideline Adherence Statistics and Numerical Data
          Male
          Middle Age
          Practice Guidelines
          Practice Patterns Statistics and Numerical Data
          Serum Albumin Administration and Dosage
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Child: 6-12 years
          Child, Preschool: 2-5 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: The appropriateness of albumin use and baseline albumin usage patterns were studied. Institutional practice patterns regarding the use of albumin were compared to criteria established by an independent expert panel. Fifty-three institutions, all of which were members of VHA or the University Health-System Consortium, participated in the evaluation. Investigators collected data over an eight-week period from the medical records, pharmacy records, and hospital billing data of adult (18 years of age or older) and pediatric (age 1-17 years) patients for whom albumin was prescribed. Data collected included patient-specific information, the prescribing physician's specialty area, patient location (level of care) when albumin was prescribed, primary reasons for prescribing albumin, and details of albumin use. Data were collected for 1649 adult and 23 pediatric patients. Albumin was prescribed inappropriately in 57.8% and appropriately in 28.2% of adults; appropriateness of use was unknown in 14% of the patients reviewed. The most common indication for albumin use was hypotension/hypovolemia (23.9%), followed by bypass-pump priming (16.3%), intradialytic blood pressure support (9.6%), and serum albumin values less than 2 g/dL (8.6%). Albumin was prescribed inappropriately 100% of the time when used for intradialytic blood pressure support, low serum albumin values, and acute respiratory distress syndrome. The most appropriate use of albumin occurred in patients with postsurgical hypotension and hypovolemia (67.8%), nephrotic syndrome (79.3%), non-hemorrhagic shock (44.3%), hemorrhagic shock (51.9%), and cirrhosis and paracentesis (31.3%). Albumin was inappropriately prescribed for 57.8% of adult patients and 52.2% of pediatric patients. The mean number of total grams used by patients receiving albumin appropriately was similar to those patients inappropriately receiving albumin.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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