Changes in cerebral blood flow in Asperger syndrome during theory of mind tasks presented by the auditory route.
Lack of theory of mind (TOM) has been considered to be a key feature in Asperger syndrome (AS). The main aim of the present study was to determine whether an exclusively auditory input of ToM stories activated the same brain areas as demonstrated previously using visual stimuli. Eight right-handed o...
| Publicado en: | European Child & Adolescent Psychiatry Vol. 12; no. 4; pp. 178 - 190 |
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| Autores principales: | , , , , , , |
| Formato: | Journal Article |
| Publicado: |
Springer Nature
2003
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106079336&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106079336 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10188827 EJ3 jtl: European Child & Adolescent Psychiatry issn: 10188827 maglogo: N pubinfo: dt: 2003 vid: 12 iid: 4 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 106079336 106079336 2009388246 10.1007/s00787-003-0337-z NLM14505068 106079336 ppf: 178 ppct: 12 formats: fmt: @attributes: type: P tig: atl: Changes in cerebral blood flow in Asperger syndrome during theory of mind tasks presented by the auditory route. aug: au: Wendt TN Metsaihonkala L Kulomaki T Aalto S Autti T Vanhala R Von Wendt L sug: subj: Asperger Syndrome Physiopathology Auditory Perception Brain Physiopathology Cerebrovascular Circulation Adult Asperger Syndrome Radiography Blood Circulation Brain Blood Supply Brain Radiography Cognition Disorders Physiopathology Imagination Male Psychological Theory Thinking Tomography, Emission-Computed Adult: 19-44 years Male ab: Lack of theory of mind (TOM) has been considered to be a key feature in Asperger syndrome (AS). The main aim of the present study was to determine whether an exclusively auditory input of ToM stories activated the same brain areas as demonstrated previously using visual stimuli. Eight right-handed otherwise healthy men with AS and eight healthy right-handed male controls participated in a PET activation study using auditory given ToM stories and stories about physical events for induction. Both subjects with AS and controls showed increased activation in the occipitotemporal area bilaterally and in thalamus during ToM tasks. Both groups also showed activation in the medial frontal area during ToM tests. However, this activation was more intensive and extensive in the control group, especially when a more sensitive analysis method was used. As a group, unrelated to the tasks, the AS subjects showed increased activation of the cerebellum. It was concluded that the activation pattern was mainly in agreement with earlier studies using comparable stimuli administered differently. There was no support for a right hemisphere specific dysfunction. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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