Rapid bone and blood flow formation in impacted morselized allografts.
5 patients were revised with impaction of morselized frozen allograft and a cemented total hip arthroplasty (THA) because of loosening and osteolysis of a primary hip arthroplasty. Plain film radiographs of the stems showed stable implants in all patients 15-24 months after surgery. The clinical res...
| Publicado en: | Acta Orthopaedica Scandinavica Vol. 74; no. 6; pp. 633 - 644 |
|---|---|
| Autores principales: | , , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Dec2003
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106080484&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106080484 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016470 1XH jtl: Acta Orthopaedica Scandinavica issn: 00016470 maglogo: Y pubinfo: dt: Dec2003 vid: 74 iid: 6 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 106080484 2009391226 NLM14763691 106080484 ppf: 633 ppct: 11 formats: fmt: @attributes: type: P tig: atl: Rapid bone and blood flow formation in impacted morselized allografts. aug: au: Sörensen J Ullmark G Längström B Nilsson O sug: subj: Neovascularization, Physiologic Osteogenesis Tomography, Emission-Computed Aged Allografts Arthroplasty, Replacement, Hip Blood Circulation Blood Volume Bone Transplantation Female Femur Blood Supply Fluorine Radioisotopes Diagnostic Use Image Processing, Computer Assisted Joint Prosthesis Male Middle Age Postoperative Period Prosthesis Failure Radiography Reoperation Aged: 65+ years Middle Aged: 45-64 years Female Male ab: 5 patients were revised with impaction of morselized frozen allograft and a cemented total hip arthroplasty (THA) because of loosening and osteolysis of a primary hip arthroplasty. Plain film radiographs of the stems showed stable implants in all patients 15-24 months after surgery. The clinical results were good. We used: 1) Positron Emission Tomography (PET) to evaluate vascularization and new bone formation in the allograft, 2) kinetic [18F]-fluoride PET to produce quantitative images, interpreted as new bone formation in the allograft surrounding the femur stem, 3) [15O]-water PET to quantify bone blood flow, and 4) [15O]-carbon monoxide to determine blood volume. After surgery, all patients were evaluated twice: at 1-8 days and 12 months and 3 patients were also studied at 4 months. As early as at 8 days after surgery, blood flow and bone formation had increased greatly adjacent to the allograft. At 4 months blood flow and bone formation were about the same, but activity was highest in the graft material. At 1 year after surgery, blood flow had declined to the levels of the contralateral femur diaphysis in most of the graft bed. These findings using the PET technique showed that angiogenesis and new bone formation occurred early after impaction of morselized bone allografts around the femoral component in revision THA. We found that PET is a sensitive method for evaluating neovascularization and bone formation in the graft beds. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|