Activity-responsive pacing produces long-term heart rate variability.
Origin of Long-term HRV. Introduction: Long-term heart rate variability (HRV) measures, including the standard deviation of means of successive 5-minute epochs of R-R interval intervals (SDANN) and the power law slope ([beta]), are important prognostic measures, yet their physiologic basis is unknow...
| Publicado en: | Journal of Cardiovascular Electrophysiology Vol. 15; no. 2; pp. 179 - 184 |
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| Autores principales: | , , , |
| Formato: | clinical trial research Journal Article |
| Publicado: |
Wiley-Blackwell
Feb2004
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106080968&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106080968 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Feb2004 vid: 15 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 106080968 2009392822 10.1111/j.1540-8167.2004.03342.x NLM15028048 106080968 ppf: 179 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Activity-responsive pacing produces long-term heart rate variability. aug: au: Raj SR Roach DE Koshman M Sheldon RS sug: subj: Cardiac Pacing, Artificial Heart Rate Physiology Motor Activity Physiology Adult Aged Clinical Trials Crossover Design Electrocardiography, Ambulatory Female Heart Block Physiopathology Heart Block Therapy Heart Conduction System Pathology Heart Conduction System Surgery Male Middle Age Pacemaker, Artificial Predictive Value of Tests Statistics Time Treatment Outcomes Human Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Origin of Long-term HRV. Introduction: Long-term heart rate variability (HRV) measures, including the standard deviation of means of successive 5-minute epochs of R-R interval intervals (SDANN) and the power law slope ([beta]), are important prognostic measures, yet their physiologic basis is unknown. We tested the hypothesis that long-term HRV arises from physical activity in a randomized cross-over study in patients with rate-responsive pacemakers. Methods and Results: Ten patients with complete heart block and dual-chamber pacemakers underwent 24-hour periods of ambulatory ECG in each of three pacing modes: atrially tracked, fixed-rate, and rate-responsive pacing. SDANN, ultralow frequency (ULF; frequencies <0.0033 Hz), and [beta] slope were calculated; and high-frequency power and root mean square of consecutive normal R-R intervals (rMSSD) were calculated as measures of short-term HRV, which have autonomic origins. Long-term HRV measures were similar with atrially tracked and rate-responsive pacing and were much greater than in fixed-rate pacing (SDANN P = 0.0001; ULF P = 0.0001; [beta] slope P = 0.0002). Short-term HRV measures were similarly low in fixed-rate and rate-responsive pacing (P = NS) and were significantly lower than with atrially tracked pacing (P = 0.0034). Conclusion: Rate-responsive pacing reproduces long-term, but not short-term, measures of HRV, suggesting that they may be markers of heart rate responses to patient activity. (J Cardiovasc Electrophysiol, Vol. 15, pp. 179-183, February 2004) pubtype: Academic Journal doctype: clinical trial research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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