Image-guided cancer therapy using PET/CT.
Functional imaging with positron emission tomography (PET) is playing an increasingly important role in the diagnosis and staging of malignant disease, image-guided therapy planning, and treatment monitoring. PET scanning with the radiolabeled glucose analogue (18)F-fluorodeoxyglucose ((18)FDG) is a...
| Publicado en: | Cancer Journal Vol. 10; no. 4; pp. 221 - 234 |
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| Autores principales: | , , , , , , , , |
| Formato: | research review Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
Jul/Aug2004
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106082962&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106082962 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 15289117 4U5 jtl: Cancer Journal issn: 15289117 maglogo: N pubinfo: dt: Jul/Aug2004 vid: 10 iid: 4 pid: 5086 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 106082962 NLM15383203 2009399739 10.1097/00130404-200407000-00003 NLM15383203 106082962 ppf: 221 ppct: 13 formats: fmt: @attributes: type: P tig: atl: Image-guided cancer therapy using PET/CT. aug: au: Yap JT Carney JP Nail NC Townsend DW Tennesse K Yap, Jeffrey T Carney, Jonathan P J Hall, Nathan C Townsend, David W affil: Department of Medicine, University of Tennessee Medical Center, Knoxville, Tennessee 37920-6999, USA sug: subj: Neoplasms Radiography Neoplasms Radiotherapy Radiation Oncology Trends Tomography, Emission-Computed Equipment and Supplies Fludeoxyglucose F 18 Diagnostic Use Neoplasm Staging Radiation Oncology Equipment and Supplies Radiopharmaceuticals Diagnostic Use Tomography, X-Ray Computed ab: Functional imaging with positron emission tomography (PET) is playing an increasingly important role in the diagnosis and staging of malignant disease, image-guided therapy planning, and treatment monitoring. PET scanning with the radiolabeled glucose analogue (18)F-fluorodeoxyglucose ((18)FDG) is a relatively recent addition to the clinically available technology for imaging cancer, complementing the more conventional anatomical imaging modalities of computed tomography (CT) and magnetic resonance (MR). These modalities are complementary in the sense that CT provides accurate localization of organs and lesions while PET maps both normal and abnormal tissue function. When combined, the two modalities can identify and localize functional abnormalities. Attempts to align CT and PET data sets with fusion software are generally successful in the brain, whereas the remainder of the body is more challenging owing to the increased number of possible degrees of freedom between the two scans. Recently these challenges have been addressed by the introduction of the combined PET/CT scanner, a hardware-oriented approach to image fusion. With this device, accurately registered anatomical and functional images can be acquired for each patient in a single scanning session. Currently, over 400 combined PET/CT scanners are installed in medical institutions worldwide, almost all of them for the diagnosis and staging of malignant disease. However, the real impact of this technology undoubtedly will be for cancer therapy, where PET/CT images will be used to guide biopsies and assist in surgical intervention, to define target volumes for radiation therapy and optimize dose, and to monitor response to chemotherapy and establish individualized patient treatment strategies. pubtype: Academic Journal doctype: research review Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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