Demand failures occurring during permanent pacing in patients with serious heart disease.

Demand failures during permanent cardiac Spacing were studied in four patients with coronary heart disease and cardiomyopathies, by means of in vivo and in vitro analyses of the pacemaker system. A common feature of the electrogram analyses (except during a second replacement in one patient), was ex...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 3; no. 1; pp. 44 - 56
Autor principal: Ohm O
Formato: case study Journal Article
Publicado: Wiley-Blackwell Jan1980
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
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        atl: Demand failures occurring during permanent pacing in patients with serious heart disease.
      aug:
        au: Ohm O
      sug:
        subj:
          Coronary Disease Physiopathology
          Myocardial Diseases Physiopathology
          Pacemaker, Artificial
          Adult
          Aged
          Death, Sudden Etiology
          Electrodes, Implanted
          Electrophysiology
          Female
          Male
          Middle Age
          Adult: 19-44 years
          Aged: 65+ years
          Middle Aged: 45-64 years
          Female
          Male
      ab: Demand failures during permanent cardiac Spacing were studied in four patients with coronary heart disease and cardiomyopathies, by means of in vivo and in vitro analyses of the pacemaker system. A common feature of the electrogram analyses (except during a second replacement in one patient), was extremely low values of amplitudes (0.77-4.36 mV) and maximum derivatives (0.16-1.06 V/sec). In spite of low electrogram amplitudes, the myocardial threshold values were low in all patients. An attempt in one patient at unipolarizing a bipolar system made the adaptation between electrogram and pulse generator more difficult. Autopsy showed that the lip of the bipolar electrode was positioned in a fibrotic area of the myocardium. The signal available for the sensing circuit will also be reduced because of voltage division between the electrode/tissue interface impedance and the input impedance of the pulse generator. Although the pulse generators used had a high input impedance (10-50 K), the tissue interface impedance may have caused a further reduction in the electrogram amplitude of 10-30%. This may have contributed to demand failure. In vitro studies confirmed that test pulses with characteristics similar to those of the electrograrns found in this investigation, were inadequate for pacemaker inhibition. Special care should be taken during electrogram recordings in patients with severe myocardial disease. One should consider the implantation of a high sensitivity pulse generator or the recently introduced sensitivity programmable pulse generators as first choice for this group of patients.
      pubtype: Academic Journal
      doctype:
        case study
        Journal Article
      ougenre: Article
    language: English
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