Maturation of the sensed electrogram amplitude over time in a new subcutaneous implantable loop recorder.

The cause of recurrent syncope may be difficult to determine if the diagnosis is not established from initial noninvasive and invasive testing. Eighteen patients with recurrent syncope and negative tilt table and electrophysiological testing underwent implantation of a left pectoral subcutaneous loo...

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Detalles Bibliográficos
Publicado en:Pacing & Clinical Electrophysiology Vol. 20; no. 6; pp. 1686 - 1691
Autores principales: Krahn AD, Klein GJ, Yee R, Norris C
Formato: Journal Article
Publicado: Wiley-Blackwell Jun1997
Acceso en línea:Ver este registro en EBSCOhost
Descripción
Sumario:The cause of recurrent syncope may be difficult to determine if the diagnosis is not established from initial noninvasive and invasive testing. Eighteen patients with recurrent syncope and negative tilt table and electrophysiological testing underwent implantation of a left pectoral subcutaneous loop recorder. This device 'freezes' the preceding 7.5 or 15 minute rhythm strip after magnet application after spontaneous syncope. Baseline and follow-up electrograms were routinely recorded, and patients were followed until syncope recurred. Three patients had syncope within 1 month of implantation and were excluded from this report. Implantation electrogram amplitude was 250 ± 124 [mu]V and increased to 291 ± 114 [mu]V at 2-3 months, and increased further to 353 ± 167 [mu]V at 4-6 months (P < 0.001, ANOVA). Syncope recurred in 14 of the 15 patients. An arrhythmic basis for syncope was established (n = 7) or excluded (n = 7) in every patient who bad recurrent syncope. All syncopal episodes were associated with diagnostic sensed electrograms. The increase in sensed electrogram amplitude over time suggests a maturation of the device-tissue interface. These results support the long-term viability of this implantable monitoring technique.