Effect of bipole configuration on atrial electrograms during atrial fibrillation.

Despite an increasing body of work on the nature of fibrillatory rhythms. and the application of different bipole configurations in antifibrillatory devices, little published work has assessed the effect of hi pole configuration on the endocardial recordings of fibrillatory rhythms. To address this...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 13; no. 1; pp. 78 - 88
Autores principales: Baerman JM, Ropella KM, Sahakian AV, Kirsh JA, Swiryn S
Formato: research Journal Article
Publicado: Wiley-Blackwell Jan1990
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jan1990
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Effect of bipole configuration on atrial electrograms during atrial fibrillation.
      aug:
        au:
          Baerman JM
          Ropella KM
          Sahakian AV
          Kirsh JA
          Swiryn S
      sug:
        subj:
          Atrial Fibrillation Physiopathology
          Electrocardiography Methods
          Heart Catheterization Equipment and Supplies
          Adolescence
          Adult
          Aged
          Aged, 80 and Over
          Cardiac Pacing, Artificial
          Electrocardiography Equipment and Supplies
          Filtration
          Heart Atrium
          Heart Rate Physiology
          Middle Age
          Prospective Studies
          Signal Processing, Computer Assisted
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Middle Aged: 45-64 years
      ab: Despite an increasing body of work on the nature of fibrillatory rhythms. and the application of different bipole configurations in antifibrillatory devices, little published work has assessed the effect of hi pole configuration on the endocardial recordings of fibrillatory rhythms. To address this issue, a specially designed 6 Fr decapolar catheter was used to record intro-a trial electrograms during sustained atrial fibrillation in 15 patients. Simultaneous filtered (30-500 Hz) and unfiltered (0.05-5.000 Hz) recordings of atrial fibrillation were performed a/four different bipole configurations; (a) 1-mm interelectrode spacing adjacent to the atrial wall: (b) 10-mm interelectrode spacing adjacent to the atrial wall: (c) 10-mm interelectrode spacing 24 mm from the distal catheter tip. (d) 1-mm interelectrode spacing 24 mm from the distal catheter tip. One minute of such data was recorded, and each 4.27-second segment (x 14 segments) was analyzed for a trial rate, electrogram amplitude, amplitude probability density function (apdf), median frequency in the 2-9 Hz band, and electrogram morphology. Changes in bipole configuration resulted in profound changes in calculated atrial rate, amplitude, and a pdf (P < 0.001 by two-way ANOVA in each instance). Specifically, closer interbipole spacing and closer proximity to the atrial wall resulted in lower calculated atrial rates, higher electrogram amplitudes, and higher apdf values. In contrast, median frequency proved to he a more robust measure despite multiple configurations (P > 0.10 by two-way ANOVA). These changes significantly affected the predictive value of previously published detection criteria for rate (P < 0.01) and apdf (P < 0.00001). Bipole location also affected morphology, with locations adjacent to the atrial wall and with closer interbipole spacing having more discrete electrograms and greater apparent organization (P < 0.0001). Further, when data segments from all patients and bipole configurations were grouped, rate and apdf were found to be strongly inversely correlated (r = 0,808). In conclusion: (1) Bipole configuration has important effects on calculated atrial rate, electrogram amplitude, and apdf during atrial fibrillation; (2) Median frequency and frequency domain analysis may be a more robust way of characterizing atrial fibrillation despite the Use of different bipole configurations; (3) Changes in bipole configuration affect the efficacy of detection criteria, and considerations about the level of organization of a cardiac rhythm; (4) Rate and apdf may be largely redundant measures of fibrillatory rhythms; and (5) Traditional estimates of atrial rates up to 700/min during atrial fibrillation, based on the unipolar or widely spaced bipolar leads of the surface electrocardiogram, reflect the effects of their recording methods. and are an overestimation of the true atrial rate.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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