Detection of atrial activation by intraventricular electrogram morphology analysis: a study to determine the feasibility of p wave synchronous pacing from a standard ventricular lead.

The detection of atrial activation from a standard ventricular pacing lead with standard ventricular electrodes would provide patients with VVI and VVIB pacing systems atrial rate response and atrial synchrony. In addition to potentially increasing cardiac output appropriately in these patients at r...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 16; no. 6; pp. 1293 - 1304
Autores principales: Greenhut SE, Svinarich JT, Randall NJ, Heald SC, Nappholz TA
Formato: research Journal Article
Publicado: Wiley-Blackwell Jun1993
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Jun1993
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Detection of atrial activation by intraventricular electrogram morphology analysis: a study to determine the feasibility of p wave synchronous pacing from a standard ventricular lead.
      aug:
        au:
          Greenhut SE
          Svinarich JT
          Randall NJ
          Heald SC
          Nappholz TA
      sug:
        subj:
          Atrioventricular Node Physiology
          Cardiac Pacing, Artificial Methods
          Heart Conduction System Physiology
          Pacemaker, Artificial
          Signal Processing, Computer Assisted
          Electrocardiography Methods
          Electrodes, Implanted
          Electrophysiology
          Female
          Male
          Middle Age
          Pilot Studies
          Sensitivity and Specificity
          Human
          Middle Aged: 45-64 years
          Female
          Male
      ab: The detection of atrial activation from a standard ventricular pacing lead with standard ventricular electrodes would provide patients with VVI and VVIB pacing systems atrial rate response and atrial synchrony. In addition to potentially increasing cardiac output appropriately in these patients at rest and during moderate exercise, P wave sensing with such a device could help reduce pacemaker syndrome. In this study, unipolar signals from distal and proximal introventricular electrodes were recorded from the right ventricular apex in 20 patients. Unipolar electrograms from 16 patients were recorded using temporary electrophysiology catheters and in four patients using permanent pacemaker leads. Approximately 3 minutes of data per patient were acquired and analyzed. After selection of a P wave template, the difference in baseline normalized area between the template and signal was calculated on a point- by-point basis. The percent of atrial depolarizations correctly detected was determined for each patient and lead configuration at the optimal threshold. Far-field P wave accuracy was better at the proximal electrode (74 ± 25%) than at the distal electrode (57 ± 34%) (P < 0.025). At the proximal electrode, 15/ 20 (75%) patients had > 70% accuracy and 11/20 (55%) patients had > 80% accuracy. At the distal electrode 10/21 (48%) patients had > 70% accuracy and 7/21 (33%) patients had > 80% accuracy, in conclusion, far-field detection of atrial activation at the ventricular proximal electrode appears possible with sufficient accuracy to provide periods of atrial rate response and synchrony in patients with a single standard lead.
      pubtype: Academic Journal
      doctype:
        research
        Journal Article
      ougenre: Article
    language: English
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