Computer aided development of antiarrhythmic agents with class iiia properties.

Most antiarrhythmic agents were discovered accidentally. In the last decade, the understanding of the mechanisms of action of agents with electrophysiologic activity has progressed greatly. As a result, it was possible to compute, before the CAST trial, that the agents selected for the trial would n...

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Bibliographic Details
Published in:Journal of Cardiovascular Electrophysiology Vol. 5; no. 8; pp. 711 - 722
Main Author: Hondeghem LM
Format: Journal Article
Published: Wiley-Blackwell Aug1994
Online Access:View this record in EBSCOhost