Electrocardiographic imaging: ii. effect of torso inhomogeneities on noninvasive reconstruction of epicardial potentials, electrograms, and isochrones.

Introduction: Noninvasive electrocardiographic imaging (ECGI) involves inverse reconstruction of epicardial potentials, electrograms (EGMs), and isochrones from body surface potential maps (BSPMs). The heart lies in a volume conductor that includes lungs, blood, bone, muscle, and fluid. We investiga...

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Publicado en:Journal of Cardiovascular Electrophysiology Vol. 12; no. 2; pp. 241 - 253
Autores principales: Ramanathan C, Rudy Y
Formato: Journal Article
Publicado: Wiley-Blackwell Feb2001
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Electrocardiographic imaging: ii. effect of torso inhomogeneities on noninvasive reconstruction of epicardial potentials, electrograms, and isochrones.
      aug:
        au:
          Ramanathan C
          Rudy Y
      sug:
        subj:
          Diagnostic Imaging
          Electrocardiography Methods
          Animals
          Cardiac Pacing, Artificial
          Computer Simulation
          Dogs
          Female
          Heart Ventricle Physiology
          Heart Physiology
          Male
          Models, Anatomic
          Reproduction
          Female
          Male
      ab: Introduction: Noninvasive electrocardiographic imaging (ECGI) involves inverse reconstruction of epicardial potentials, electrograms (EGMs), and isochrones from body surface potential maps (BSPMs). The heart lies in a volume conductor that includes lungs, blood, bone, muscle, and fluid. We investigate the effects of these torso inhomogeneities on reconstructed epicardial potentials, EGMs, and isochrones to address the issue of whether they should he included in clinical ECGI methodology. Methods and Results: Potential data were obtained for different pacing protocols from a dog heart suspended in a human-shaped torso tank. .Accurate geometry of torso inhomogeneities was digitized from the Visual Human Project and appropriately introduced into a computer model of the torso. Three models were used: accurate inhomogeneous torso, homogeneous torso, and a torso with stylized lungs {to generate an approximate model). The inhomogeneous model was used to compute BSPMs from the measured epicardial potentials. These BSPMs were the starting point for inverse computations in the different torso models. Epicardial potential maps, EGMs, and isochrones were computed. The homogeneous model produced slightly less accurate epicardial potential reconstructions than the inhomogeneous model and stylized lung model, but epicardial potential patterns, EGMs, isochrones, and locations of pacing sites were reconstructed with comparable accuracy when torso inhomogeneities were ignored. Conclusion: The results demonstrate that, in the clinical application, it is not necessary to include torso inhomogeneities for noninvasive reconstructions of epicardial potentials, EGMs, and activation sequences.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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