Effect of MKC-733, a 5-HT3 receptor partial agonist, on bowel motility and symptoms in subjects with constipation: an exploratory study.

Background: MKC-733, a 5-HT3 receptor partial agonist, is a novel enteroprokinetic compound. Objective: The aim of this study was to explore the effects of MKC-733 on bowel motility and symptoms in a small group of subjects with constipation. Tolerability was also examined. Methods: The study was co...

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Detalles Bibliográficos
Publicado en:Journal of Clinical Pharmacy & Therapeutics Vol. 30; no. 6; pp. 611 - 623
Autores principales: Fujita T, Yokota S, Sawada M, Majima M, Ohtani Y, Kumagai Y
Formato: clinical trial research Journal Article
Publicado: Wiley-Blackwell Dec2005
Acceso en línea:Ver este registro en EBSCOhost