Behavioral states and sudden cardiac death.

Remarkable progress has been made both experimentally and clinically in defining the influence of behavioral states on susceptibility to life-threatening arrhythmias. Biological models have been developed to emulate anger and fear and have permitted detailed study of the intermediary mechanisms invo...

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Publicado en:Pacing & Clinical Electrophysiology Vol. 15; no. 9; pp. 1387 - 1394
Formato: Journal Article
Publicado: Wiley-Blackwell Sep1992
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Sep1992
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      pub: Wiley-Blackwell
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        atl: Behavioral states and sudden cardiac death.
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        subj:
          Behavior
          Death, Sudden, Cardiac
          Emotions
          Stress, Psychological Physiopathology
          Anger
          Animals
          Arrhythmia Physiopathology
          Cardiovascular System Physiopathology
          Dogs
          Fear
          Myocardial Ischemia Physiopathology
          Polysomnography
          Sleep Physiology
      ab: Remarkable progress has been made both experimentally and clinically in defining the influence of behavioral states on susceptibility to life-threatening arrhythmias. Biological models have been developed to emulate anger and fear and have permitted detailed study of the intermediary mechanisms involved in stress-induced ischemia and ventricular fibrillation. The studies highlight the importance of adrenergic factors and the pathological significance of the poststress state. Clinically, the role of daily stresses in inducing silent myocardial ischemia and arrhythmias has been extensively characterized, and standardized behavioral stress tests have become available. Certain sleep states have been found to provoke ischemic episodes and arrhythmias. In particular, phasic rapid eye movement (REM) sleep has been shown both in animals and humans to conduce to perfusion abnormalities and propensity to fibrillation. Episodic surges in sympathetic nervous system activity appear to be the underlying basis. These conceptual and practical advances illustrate the promise of behavioral cardiology in the diagnosis and treatment of individuals at risk for sudden cardiac death.
      pubtype: Academic Journal
      doctype: Journal Article
      ougenre: Article
    language: English
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