Equipose and international human-subjects research.

This paper examines the role of equipoise in evaluating international research. It distinguishes two possible formulations of the equipoise requirement that license very different evaluations of international research proposals. The interpretation that adopts a narrow criterion of similarity between...

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Publicado en:Bioethics Vol. 15; no. 4; pp. 312 - 333
Autor principal: London AJ
Formato: research Journal Article
Publicado: Wiley-Blackwell Aug2001
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Equipose and international human-subjects research.
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          Clinical Trials Standards
          Developing Countries
          Ethics
          International Relations
          Research, Medical
          Study Design
          Uncertainty
          Developed Countries
          Expectant Mothers
          Female
          HIV Infections Prevention and Control
          HIV Infections
          Placebos
          Pregnancy
          Research Subjects
          Uganda
          United States
          Zidovudine
          Human
          Female
      ab: This paper examines the role of equipoise in evaluating international research. It distinguishes two possible formulations of the equipoise requirement that license very different evaluations of international research proposals. The interpretation that adopts a narrow criterion of similarity between clinical contexts has played an important role in one recent controversy, but it suffers from a number of problems. An alternative interpretation that adopts a broader criterion of similarity does a better job of avoiding both exploitation of the brute fact of social deprivation and the exploitation of needy populations for the benefit of more well-off populations. It also holds out the promise of reconciling the need to find interventions that can be employed in developing world contexts with the cluster of moral values that must constrain the way such research is carried out.
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    language: English
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