Olfactory function in HIV-positive subjects.
The aim of this study was to reinvestigate previous reports of chemosensory dysfunction in HIV-positive subjects. Odor thresholds, odor discrimination and odor identification were assessed using the Sniffin' Sticks test battery. Seventy-four HIV-positive patients were tested. According to CDC criter...
| Publicado en: | Acta Oto-Laryngologica Vol. 122; no. 1; pp. 67 - 72 |
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| Autores principales: | , , , , |
| Formato: | research Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jan2002
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106095822&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106095822 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016489 B6D jtl: Acta Oto-Laryngologica issn: 00016489 maglogo: Y pubinfo: dt: Jan2002 vid: 122 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 106095822 2009443103 10.1080/00016480252775760 NLM11878282 106095822 ppf: 67 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Olfactory function in HIV-positive subjects. aug: au: Mueller C Temmel AF Quint C Rieger A Hummel T sug: subj: HIV Infections Physiopathology Olfaction Disorders Diagnosis Smell Physiology Adult AIDS-Related Opportunistic Infections Complications Case Control Studies Cognition Disorders Complications Female HIV Infections Complications Male Odors Olfaction Disorders Complications Perception Human Adult: 19-44 years Female Male ab: The aim of this study was to reinvestigate previous reports of chemosensory dysfunction in HIV-positive subjects. Odor thresholds, odor discrimination and odor identification were assessed using the Sniffin' Sticks test battery. Seventy-four HIV-positive patients were tested. According to CDC criteria, 38 subjects were classified as stage A, 10 as stage B and 26 as stage C. None of the subjects exhibited severe cognitive impairment. Compared to normative data all subjects had normal odor identification and discrimination. However, odor thresholds were well below the median of a normal population. There were no significant differences between stage A, B or C subjects. This may be interpreted as indicating that olfactory dysfunction is among the primary deficits of HIV infection and occurs independently of disease stage. These results confirm previous work suggesting that odor thresholds are elevated early in HIV infection whereas a decline in identification and discrimination abilities is correlated with reduced cognitive abilities. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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