Predictive genetic testing: mediators and moderators of anxiety.

Mediators and moderators of anxiety following predictive genetic testing were investigated in a cross-sectional study of 208 individuals at risk for familial adenomatous polyposis (FAP). Receiving a positive test result was associated with increased anxiety. The relationship between test result and...

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Publicado en:International Journal of Behavioral Medicine Vol. 9; no. 4; pp. 309 - 322
Autores principales: Michie S, French DP, Marteau TM
Formato: research Journal Article
Publicado: Springer Nature Dec2002
Acceso en línea:Ver este registro en EBSCOhost
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        atl: Predictive genetic testing: mediators and moderators of anxiety.
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          Michie S
          French DP
          Marteau TM
      sug:
        subj:
          Anxiety Diagnosis
          Anxiety
          Adolescence
          Adult
          Cross Sectional Studies
          Female
          Male
          Predictive Value of Tests
          Questionnaires
          Self Concept
          Severity of Illness Indices
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Female
          Male
      ab: Mediators and moderators of anxiety following predictive genetic testing were investigated in a cross-sectional study of 208 individuals at risk for familial adenomatous polyposis (FAP). Receiving a positive test result was associated with increased anxiety. The relationship between test result and anxiety was mediated by how threatened individuals felt by their test results. The impact of a positive test result was greater for those who felt distressed about FAP in their families, perceived FAP to be more serious, and perceived the genetic test to be more accurate. The results suggest that assessing, and possibly modifying, people's appraisals of the condition and of its impact on the family and of the threat of the genetic test may help to reduce subsequent anxiety. This has implications for the practice of genetic counseling.
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        research
        Journal Article
      ougenre: Article
    language: English
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