Vitamin a-storing stellate cells in the human vocal fold.
OBJECTIVE: Previously, we discovered cells with a star-like appearance that constantly synthesized extracellular matrices in the human adult vocal fold mucosa. These cells had no nomenclature and were thus designated 'vocal fold stellate cells (VFSC)'. The aim of the present study was to detect vita...
| Publicado en: | Acta Oto-Laryngologica Vol. 123; no. 1; pp. 106 - 111 |
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| Autores principales: | , , |
| Formato: | Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jan2003
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106099804&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106099804 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016489 B6D jtl: Acta Oto-Laryngologica issn: 00016489 maglogo: Y pubinfo: dt: Jan2003 vid: 123 iid: 1 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 106099804 2009458540 NLM12625583 106099804 ppf: 106 ppct: 5 formats: fmt: @attributes: type: P tig: atl: Vitamin a-storing stellate cells in the human vocal fold. aug: au: Sato K Hirano M Nakashima T sug: subj: Laryngeal Mucosa Pathology Vitamin A Metabolism Vocal Cords Cells Pathology Female Hypopharyngeal Neoplasms Male Microscopy Middle Age Tongue Neoplasms Pathology Middle Aged: 45-64 years Female Male ab: OBJECTIVE: Previously, we discovered cells with a star-like appearance that constantly synthesized extracellular matrices in the human adult vocal fold mucosa. These cells had no nomenclature and were thus designated 'vocal fold stellate cells (VFSC)'. The aim of the present study was to detect vitamin A (retinol) in the VFSC. MATERIAL AND METHODS: Five normal human adult vocal folds obtained from surgical specimens were used. Light microscopy using the gold chloride method and fluorescence microscopy were used to detect vitamin A. RESULTS: VFSC distributed in the maculae flavae of human adult vocal folds possessed lipid droplets and stored vitamin A. CONCLUSION: It is generally accepted that vitamin A, an essential liposoluble vitamin, is used as a morphogen that controls the differentiation and morphogenesis of cells. In our previous investigation and in this study VFSC were found to differ morphologically from conventional fibroblasts. VFSC represent morphologically a new category of cells in the human vocal fold. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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