Cardiovascular conditioning and anticipatory nausea and vomiting in cancer patients.
Explanations of individual differences in susceptibility to learning of anticipatory nausea and/or vomiting (AN/V) in cancer patients have focused mainly on the patients who develop AN/V. On the basis of conditioning theory, however, one would expect that all patients who experience post-treatment n...
| Publicado en: | Behavioral Medicine Vol. 20; no. 2; pp. 78 - 79 |
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| Autores principales: | , |
| Formato: | research Journal Article |
| Publicado: |
Taylor & Francis Ltd
Summer1994
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106101487&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106101487 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 08964289 BMD jtl: Behavioral Medicine issn: 08964289 maglogo: N pubinfo: dt: Summer1994 vid: 20 iid: 2 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 106101487 2009468457 10.1080/08964289.1994.9934620 NLM7803940 106101487 ppf: 78 ppct: 1 formats: fmt: @attributes: type: T tig: atl: Cardiovascular conditioning and anticipatory nausea and vomiting in cancer patients. aug: au: Kvale G Psychol C sug: subj: Anticipatory Nausea and Vomiting Physiopathology Arousal Physiology Autonomic Nervous System Physiopathology Conditioning (Psychology) Nausea Physiopathology Adolescence Adult Aged Anticipatory Nausea and Vomiting Psychosocial Factors Antineoplastic Agents, Combined Adverse Effects Antineoplastic Agents, Combined Therapeutic Use Female Heart Rate Physiology Male Middle Age Nausea Chemically Induced Nausea Psychosocial Factors Neoplasms Drug Therapy Neoplasms Physiopathology Neoplasms Psychosocial Factors Prospective Studies Psychomotor Performance Reaction Time Physiology Human Adolescent: 13-18 years Adult: 19-44 years Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Explanations of individual differences in susceptibility to learning of anticipatory nausea and/or vomiting (AN/V) in cancer patients have focused mainly on the patients who develop AN/V. On the basis of conditioning theory, however, one would expect that all patients who experience post-treatment nausea and/or vomiting (PN/V) should develop AN/V. Consistent with findings demonstrating that conditioned responses are more easily established in autonomic-reactive individuals, we have previously reported that patients who do not develop AN/V (noAN/V) are less autonomic reactive than the AN/V patients. Thus, we hypothesized that the noAN/V patients might not show classical conditioning to the same degree and extent as the AN/V patients and that conditioning may be the mediating mechanism in AN/V. This study presents data from 36 patients. Among the 28 patients who experienced PN/V, 16 developed AN/V. We found no systematic group differences in severity of PN/V or antiemetic treatment. Before chemotherapy, all patients were tested in a signaled reaction-time paradigm. We used two different tones (CSs), one of which was always followed by a noise (UCS) as a button-press signal. The patients who later developed AN/V demonstrated significantly shorter reaction times, and also showed enhanced cardiovascular reactivity to the tone followed by the UCS (CS+) in comparison with the nonsignal tone (CS-). The noAN/V patients did not show differential cardiovascular responses to the CS+ and CS-. pubtype: Academic Journal doctype: research Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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