Gene profiling of scleroderma skin reveals robust signatures of disease that are imperfectly reflected in the transcript profiles of explanted fibroblasts.

OBJECTIVE: To determine whether biopsy specimens obtained from systemic sclerosis (SSc) lesions show a distinctive gene profile, whether that gene profile is maintained in fibroblasts cultured from SSc skin biopsy specimens, and whether results from tissue obtained from multiple clinical centers can...

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Publicado en:Arthritis & Rheumatism Vol. 54; no. 6; pp. 1961 - 1974
Autores principales: Gardner H, Shearstone JR, Bandaru R, Crowell T, Lynes M, Trojanowska M, Pannu J, Smith E, Jablonska S, Blaszczyk M, Tan FK, Mayes MD
Formato: pictorial research tables/charts Journal Article
Publicado: Wiley-Blackwell 2006 Jun
Acceso en línea:Ver este registro en EBSCOhost