Severity of Alzheimer's disease and effect on premorbid measures of intelligence.

Objectives. To assess the robustness of the National Adult Reading Test (NART), Wechsler Test of Adult Reading (WTAR), Cambridge Contextual Reading Test (CCRT), Spot the Word (STW), and a demographic regression equation in estimating premorbid ability in people with Alzheimer's disease (AD). Design....

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Publicado en:British Journal of Clinical Psychology Vol. 45; no. 4; pp. 453 - 464
Autores principales: McFarlane J, Welch J, Rodgers J
Formato: research tables/charts Journal Article
Publicado: Wiley-Blackwell Nov2006
Acceso en línea:Ver este registro en EBSCOhost
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      dt: Nov2006
      vid: 45
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      pub: Wiley-Blackwell
      place: Malden, Massachusetts
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        atl: Severity of Alzheimer's disease and effect on premorbid measures of intelligence.
      aug:
        au:
          McFarlane J
          Welch J
          Rodgers J
        affil: Acute Division, Rehabilitation and Assessment Directorate, Greater Glasgow and Clyde Healthboard
      sug:
        subj:
          Alzheimer's Disease Diagnosis
          Alzheimer's Disease Epidemiology
          Cognition Disorders Diagnosis
          Cognition Disorders Epidemiology
          Aged
          Analysis of Variance
          Chi Square Test
          Cross Sectional Studies
          Descriptive Statistics
          Disease Progression
          Female
          Intelligence
          Male
          Neuropsychological Tests
          P-Value
          Quasi-Experimental Studies
          Reading
          Regression
          Sample Size
          Severity of Illness Indices
          Time Factors
          Human
          Aged: 65+ years
          Female
          Male
      ab: Objectives. To assess the robustness of the National Adult Reading Test (NART), Wechsler Test of Adult Reading (WTAR), Cambridge Contextual Reading Test (CCRT), Spot the Word (STW), and a demographic regression equation in estimating premorbid ability in people with Alzheimer's disease (AD). Design. A cross-sectional multiple measures design. Method. Sixty-six probable AD participants were classified into stages of severity according to their Mini Mental State Examination (MMSE) score (minimal 24 to 28; mild 14 to 23). Their scores on the NART, WTAR, CCRT, STW and a demographic equation were compared with 32 healthy age matched controls. Results. Significant between-group differences were found for the tests of reading ability (NART, WTAR and CCRT). The mild group made significantly more errors than the control and minimal groups. For the mild group, there was an advantage of putting the NART words into context (CCRT), but this group still made significantly more errors than the control and minimal groups. The NART was compared with the demographic estimate and there was a significant difference for the mild group with the demographic estimate providing a higher estimate. This was not the case for the control or minimal groups. There was no significant difference between the groups on the lexical decision task (STW). Conclusion. Reading of irregular words is compromised in AD for those with a MMSE score in the range of 14 to 23. A lexical decision task may provide a more accurate estimate of premorbid intelligence in those with mild AD. Further research is needed to provide evidence of STW's correlation with current ability.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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