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Effect of age and sex on heart rate variability in healthy subjects.

OBJECTIVE: The study aimed to investigate the effect of age and sex on the heart rate variability (HRV) analysis and to explore the normal range of HRV in different age and sex groups for potential health care applications. METHOD: Baseline HRV, age, and sex data were collected from 470 subjects wit...

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Published in:Journal of Manipulative & Physiological Therapeutics Vol. 30; no. 5; pp. 374 - 380
Main Author: Zhang J
Format: research tables/charts Journal Article
Published: Elsevier B.V. Jun2007
Online Access:View this record in EBSCOhost
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      issn: 01614754
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      dt: Jun2007
      vid: 30
      iid: 5
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      pub: Elsevier B.V.
      place: Philadelphia, Pennsylvania
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        106139292
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        10.1016/j.jmpt.2007.04.001
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      tig:
        atl: Effect of age and sex on heart rate variability in healthy subjects.
      aug:
        au: Zhang J
        affil: Logan College of Chiropractic, Chesterfield, MO 63017, USA. john.zhang@logan.edu
      sug:
        subj:
          Age Factors
          Heart Rate
          Sex Factors
          Adolescence
          Adult
          Aged
          Aged, 80 and Over
          Analysis of Variance
          Child
          Data Analysis Software
          Data Analysis, Statistical
          Descriptive Statistics
          Electrocardiography
          Female
          Male
          Middle Age
          P-Value
          Paired T-Tests
          Retrospective Design
          Human
          Adolescent: 13-18 years
          Adult: 19-44 years
          Aged: 65+ years
          Aged, 80 & over
          Child: 6-12 years
          Middle Aged: 45-64 years
          Female
          Male
      ab: OBJECTIVE: The study aimed to investigate the effect of age and sex on the heart rate variability (HRV) analysis and to explore the normal range of HRV in different age and sex groups for potential health care applications. METHOD: Baseline HRV, age, and sex data were collected from 470 subjects without cardiovascular conditions. Short-term HRV was recorded using Biocom Active ECG units (Biocom, Seattle, Wash). Subjects were divided by age into 10-year intervals and by sex for HRV analysis. RESULTS: Total power, representing the overall autonomic activity, decreased consistently from the age groups 10+ to 80+ years (P < .001). Both the low frequency (sympathetic activity) and high frequency (parasympathetic activity) declined (P < .05) as age increased. Sex had a significant effect on heart rate, R-R interval, high frequency, normalized low frequency, normalized high frequency, and low frequency-high frequency ratio. Sex did not seem to affect the SD of the normal-to-normal heartbeats and total power (P > .05) despite the significant heart rate changes (P < .05). CONCLUSION: This study demonstrated that age had a greater impact on HRV than sex. The older age group had consistently lower HRV than younger people. The values generated in this study may be useful in health care settings to determine abnormal ranges of HRV under different clinical and experimental conditions.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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