Occupation and parkinsonism in three movement disorders clinics.
BACKGROUND: Few occupational risk factors for Parkinson disease (PD) have been identified. Healthcare, teaching, and farming have been associated with increased risk, while welding has been proposed to accelerate age at PD onset. The aim of the present study was to investigate occupational associati...
| Publicado en: | Neurology Vol. 65; no. 9; pp. 1430 - 1436 |
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| Autores principales: | , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Lippincott Williams & Wilkins
2005 Nov 8
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106150174&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106150174 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00283878 NRO jtl: Neurology issn: 00283878 maglogo: N pubinfo: dt: 2005 Nov 8 vid: 65 iid: 9 pid: 433 pub: Lippincott Williams & Wilkins place: Baltimore, Maryland artinfo: ui: 106150174 106150174 2009530974 10.1212/01.wnl.0000180361.74060.70 NLM16162857 106150174 ppf: 1430 ppct: 6 formats: tig: atl: Occupation and parkinsonism in three movement disorders clinics. aug: au: Goldman SM Tanner CM Olanow CW Watts RL Field RD Langston JW affil: The University of California, San Francisco, CA, USA. sgoldman@thepi.org sug: subj: Environmental Exposure Occupational Exposure Occupations and Professions Parkinson Disease Epidemiology Adult Age Factors Age of Onset Aged Aged, 80 and Over Ambulatory Care Facilities Causal Attribution Chi Square Test Data Analysis Software Data Analysis, Statistical Female Male Mann-Whitney U Test Middle Age Multicenter Studies Post Hoc Analysis Risk Factors Selection Bias T-Tests Two-Tailed Test United States Human Adult: 19-44 years Aged: 65+ years Aged, 80 & over Middle Aged: 45-64 years Female Male ab: BACKGROUND: Few occupational risk factors for Parkinson disease (PD) have been identified. Healthcare, teaching, and farming have been associated with increased risk, while welding has been proposed to accelerate age at PD onset. The aim of the present study was to investigate occupational associations with PD or parkinsonism drawing from three different movement disorders clinics. METHODS: Medical records of 2,249 consecutive patients with PD or parkinsonism from specialty clinics in Sunnyvale, CA, New York, NY, and Atlanta, GA, were reviewed for primary lifetime occupation. Job frequencies were compared with Department of Labor regional statistics. PD diagnosis age and risk of diagnosis < or =50 were determined for each job. RESULTS: Physicians/dentists, farmers, and teachers were significantly more common than expected among PD patients, as were lawyers, scientists, and religion-related jobs. Computer programmers had a younger age at PD diagnosis, and risk of diagnosis < or =50 was greater in computer programmers and technicians. CONCLUSIONS: Consistent with prior studies, healthcare, teaching, and farming were common occupations in Parkinson disease (PD) patients, but welders were not over-represented. Even though several occupations were associated with younger age at PD diagnosis, these results may reflect biases inherent in specialty clinic surveys, including over-representation of younger, employed, and insured patients. Carefully designed analytic studies utilizing appropriate control populations will be required to test hypotheses regarding occupation and PD risk. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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