White matter fiber tracking computation based on diffusion tensor imaging for clinical applications.

Fiber tracking allows the in vivo reconstruction of human brain white matter fiber trajectories based on magnetic resonance diffusion tensor imaging (MR-DTI), but its application in the clinical routine is still in its infancy. In this study, we present a new software for fiber tracking, developed o...

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Publicado en:Journal of Digital Imaging Vol. 20; no. 1; pp. 88 - 98
Autores principales: Dellani PR, Glaser M, Wille PR, Vucurevic G, Stadie A, Bauermann T, Tropine A, Perneczky A, von Wangenheim A, Stoeter P
Formato: diagnostic images pictorial research tables/charts Journal Article
Publicado: Springer Nature Mar2007
Acceso en línea:Ver este registro en EBSCOhost
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      pub: Springer Nature
      place: New York, New York
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          Dellani PR
          Glaser M
          Wille PR
          Vucurevic G
          Stadie A
          Bauermann T
          Tropine A
          Perneczky A
          von Wangenheim A
          Stoeter P
        affil: Institute of Neuroradiology, Johannes Gutenberg-University of Mainz, Langenbeckstrasse 1, 55131, Mainz, Germany.
      sug:
        subj:
          Brain Radiography
          Diagnostic Imaging Methods
          Neurosurgery Methods
          Algorithms
          DICOM
          Picture Archiving and Communication Systems
          Software
          Human
      ab: Fiber tracking allows the in vivo reconstruction of human brain white matter fiber trajectories based on magnetic resonance diffusion tensor imaging (MR-DTI), but its application in the clinical routine is still in its infancy. In this study, we present a new software for fiber tracking, developed on top of a general-purpose DICOM (digital imaging and communications in medicine) framework, which can be easily integrated into existing picture archiving and communication system (PACS) of radiological institutions. Images combining anatomical information and the localization of different fiber tract trajectories can be encoded and exported in DICOM and Analyze formats, which are valuable resources in the clinical applications of this method. Fiber tracking was implemented based on existing line propagation algorithms, but it includes a heuristic for fiber crossings in the case of disk-shaped diffusion tensors. We successfully performed fiber tracking on MR-DTI data sets from 26 patients with different types of brain lesions affecting the corticospinal tracts. In all cases, the trajectories of the central spinal tract (pyramidal tract) were reconstructed and could be applied at the planning phase of the surgery as well as in intraoperative neuronavigation.
      pubtype: Academic Journal
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        pictorial
        research
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        Journal Article
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    language: English
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