A disconnection syndrome due to agenesis of the corpus callosum: disturbance of unilateral synchronization.
Recently, interhemispheric disconnection syndromes have been noted in patients with agenesis of the corpus callosum (ACC) during the performance of certain tasks. However, few studies have demonstrated an asymmetric disconnection syndrome. In this report, we present just such a syndrome in a patient...
| Publicado en: | Cortex: A Journal Devoted to the Study of the Nervous System & Behavior Vol. 42; no. 3; pp. 356 - 366 |
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| Autores principales: | , , , , , |
| Formato: | case study diagnostic images research tables/charts Journal Article |
| Publicado: |
Masson SPA
Apr2006
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106157914&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106157914 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00109452 GMP jtl: Cortex: A Journal Devoted to the Study of the Nervous System & Behavior issn: 00109452 maglogo: N pubinfo: dt: Apr2006 vid: 42 iid: 3 pid: 12473 pub: Masson SPA artinfo: ui: 106157914 106157914 NLM16771041 2009205281 NLM16771041 106157914 ppf: 356 ppct: 10 formats: tig: atl: A disconnection syndrome due to agenesis of the corpus callosum: disturbance of unilateral synchronization. aug: au: Midorikawa A Kawamura M Takaya R Midorikawa, Akira Kawamura, Mitsuru Takaya, Rieko affil: Department of Animal Models for Human Disease, National Institute of Neuroscience, National Center of Neurology and Psychiatry - NCNP, Tokyo, Japan sug: subj: Agenesis of Corpus Callosum Dominance, Cerebral Physiology Motor Skills Reaction Time Physiology Adult Analysis of Variance Case Studies Clinical Assessment Tools Comparative Studies Data Collection, Computer Assisted Dominance, Cerebral Female Funding Source Human Intelligence Tests Language Tests Movement Physiology Neural Pathways Physiology Neuropsychological Tests Perception Post Hoc Analysis Random Sample Reaction Time Reference Values Scales Tomography, X-Ray Computed Two-Way Analysis of Variance Wechsler Adult Intelligence Scale-Revised Wechsler Memory Scale-Revised Adult: 19-44 years Female ab: Recently, interhemispheric disconnection syndromes have been noted in patients with agenesis of the corpus callosum (ACC) during the performance of certain tasks. However, few studies have demonstrated an asymmetric disconnection syndrome. In this report, we present just such a syndrome in a patient with ACC, who manifested ambidexterity (but with a left-hand tendency) and had high intelligence, no neurological deficits, and no associated malformations. In a comparison with similar subjects (amateur musician), we studied her asymmetric deficits using four tasks: (1) simple reaction time for visual stimuli, (2) paced finger tapping in synchrony with visual or auditory stimuli, (3) paced finger tapping without an external reference, and (4) rhythmical finger tapping in synchrony with visual or auditory stimuli. While the comparable subjects displayed no significant difference between hands, and the patient showed no significant difference between hands in the auditory paradigm, her tapping performance deteriorated significantly when asked to synchronize the left hand with timed visual stimuli, irrespective of whether finger tapping was paced or rhythmical. We believe that this phenomenon constitutes a novel asymmetrical disconnection syndrome in an ACC subject; these results suggest that synchronization of multimodal temporal information was lateralized in the left hemisphere (in this case), which is something that the ACC patient could not compensate for. pubtype: Academic Journal doctype: case study diagnostic images research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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