Gastric MALT lymphoma: clinical characteristics and prevalence of H. pylori infection in a series of 37 cases.
OBJECTIVE: to perform a retrospective review of the clinical characteristics and prevalence of H. pylori infection in patients with gastric MALT lymphoma diagnosed in our hospital during the last 15 years. METHODS: patients with gastric MALT lymphoma diagnosed in our hospital during the last 15 year...
| Publicado en: | Spanish Journal of Gastroenterology / Revista Española de Enfermedades Digestivas Vol. 98; no. 9; pp. 655 - 666 |
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| Autores principales: | , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Aran Ediciones S.A.
2006 Sep
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| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106177801&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106177801 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 11300108 YU3 jtl: Spanish Journal of Gastroenterology / Revista Española de Enfermedades Digestivas issn: 11300108 maglogo: N pubinfo: dt: 2006 Sep vid: 98 iid: 9 pid: 20394 pub: Aran Ediciones S.A. artinfo: ui: 106177801 106177801 2009679123 NLM17092197 106177801 ppf: 655 ppct: 11 formats: tig: atl: Gastric MALT lymphoma: clinical characteristics and prevalence of H. pylori infection in a series of 37 cases. aug: au: Gisbert JP Aguado B Luna M Nistal S Asenjo LM Reina T Acevedo A Arranz R affil: Servides of Gastroenterology, Hospital Universitario de La Princesa. Universidad Autónoma. Madrid, Spain. gisbert@meditex.es sug: subj: Helicobacter Infections Complications Lymphoma, B-Cell Prevention and Control Lymphoma, Non-Hodgkin's Prevention and Control Stomach Neoplasms Prevention and Control Aged Breath Tests Utilization Clinical Assessment Tools Confidence Intervals Descriptive Research False Negative Results Female Funding Source Helicobacter Infections Epidemiology Histocytochemistry Methods Lymphoma, B-Cell Complications Lymphoma, B-Cell Diagnosis Lymphoma, Non-Hodgkin's Complications Lymphoma, Non-Hodgkin's Diagnosis Male Middle Age Power Analysis Prevalence Qualitative Studies Retrospective Design Severity of Illness Indices Stomach Neoplasms Complications Stomach Neoplasms Diagnosis Human Aged: 65+ years Middle Aged: 45-64 years Female Male ab: OBJECTIVE: to perform a retrospective review of the clinical characteristics and prevalence of H. pylori infection in patients with gastric MALT lymphoma diagnosed in our hospital during the last 15 years. METHODS: patients with gastric MALT lymphoma diagnosed in our hospital during the last 15 years were retrospectively included. Demographic, clinic, analytic, endoscopic, and histological variables were reviewed. The extension study, the staging classification, and the presence of H. pylori infection were assessed. RESULTS: thirty-seven patients with gastric MALT lymphoma were identified. Mean age was 61 years, with 62% of males. The most common presentation symptom was dyspepsia (76%), followed by digestive bleeding (11%) and constitutional syndrome (8%). At endoscopy, erosive lesions were identified in 41%, and proliferative or exophytic lesions in 43%. Most lymphomas were classified as low-grade (68%). The stage distribution was EI for 56%, EII for 13%, EIII for 3%, and EIV for 28%. The prevalence of H. pylori infection (histology in all cases, rapid urease test in 19%, and 13C-urea breath test in 24%) was 46%. When only low-grade lymphomas in stage EI were considered, H. pylori prevalence increased to 55%. When H. pylori infection was evaluated by 13C-urea breath testing (in addition to histology), the prevalence of H. pylori infection increased to 78%. CONCLUSIONS: it is probable that the reduced H. pylori prevalence found in some studies, as in ours, could be explained by false-negative results obtained when only one diagnostic method was used. Therefore, at least two (invasive) diagnostic methods should be performed. Furthermore, the performance of a non-invasive diagnostic method (such as a 13C-urea breath test) before the exclusion of H. pylori infection should be considered. pubtype: Periodical doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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