Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report.
At the request of the U.S. Environmental Protection Agency (EPA) Office of Research and Development, a subcommittee of the Board of Scientific Counselors Executive Committee conducted an independent and open peer review of the Endocrine Disrupting Chemicals Research Program (EDC Research Program) of...
| Published in: | Environmental Health Perspectives Vol. 114; no. 8; pp. 1276 - 1283 |
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| Main Authors: | , , , , , , , |
| Format: | Journal Article |
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National Institute of Environmental Health Sciences
Aug2006
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106178272&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106178272 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00916765 3B5 jtl: Environmental Health Perspectives issn: 00916765 maglogo: N pubinfo: dt: Aug2006 vid: 114 iid: 8 pid: 56539 pub: National Institute of Environmental Health Sciences place: Research Triangle Park, North Carolina artinfo: ui: 106178272 106178272 2009258036 10.1289/ehp.8875 NLM16882539 106178272 ppf: 1276 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Endocrine disrupting chemicals research program of the U.S. Environmental Protection Agency: summary of a peer-review report. aug: au: Harding AK Daston GP Boyd GR Lucier GW Safe SH Stewart J Tillitt DE Van Der Kraak G affil: Department of Public Health, Oregon State University, Corvallis, Oregon, USA. sug: subj: Endocrine System Drug Effects Environmental Pollutants Adverse Effects Organizational Objectives Peer Review Research United States United States Environmental Protection Agency ab: At the request of the U.S. Environmental Protection Agency (EPA) Office of Research and Development, a subcommittee of the Board of Scientific Counselors Executive Committee conducted an independent and open peer review of the Endocrine Disrupting Chemicals Research Program (EDC Research Program) of the U.S. EPA. The subcommittee was charged with reviewing the design, relevance, progress, scientific leadership, and resources of the program. The subcommittee found that the long-term goals and science questions in the EDC Program are appropriate and represent an understandable and solid framework for setting research priorities, representing a combination of problem-driven and core research. Long-term goal (LTG) 1, dealing with the underlying science surrounding endocrine disruptors, provides a solid scientific foundation for conducting risk assessments and making risk management decisions. LTG 2, dealing with defining the extent of the impact of endocrine-disrupting chemicals (EDCs) , has shown greater progress on ecologic effects of EDCs compared with that on human health effects. LTG 3, which involves support of the Endocrine Disruptor Screening and Testing Program of the U.S. EPA, has two mammalian tests already through a validation program and soon available for use. Despite good progress, we recommend that the U.S. EPA a) strengthen their expertise in wildlife toxicology, b) expedite validation of the Endocrine Disruptors Screening and Testing Advisory Committee tests, c) continue dependable funding for the EDC Research Program, d) take a leadership role in the application of 'omics' technologies to address many of the science questions critical for evaluating environmental and human health effects of EDCs, and e) continue to sponsor multidisciplinary intramural research and interagency collaborations. pubtype: Academic Journal doctype: Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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