Acute evaluation of programmer-guided AV/PV and VV delay optimization comparing an IEGM method and echocardiogram for cardiac resynchronization therapy in heart failure patients and dual-chamber ICD implants.
Introduction: Intracardiac delay optimization of biventricular and dual-chamber pacing devices currently relies on time-consuming echocardiographic measurements. A novel intracardiac electrogram (IEGM) method for atrioventricular (AV/PV) and interventricular (VV) delay optimization was developed, wh...
| Published in: | Journal of Cardiovascular Electrophysiology Vol. 18; no. 2; pp. 185 - 192 |
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| Main Authors: | , , , , , , , , , , |
| Format: | clinical trial research tables/charts Journal Article |
| Published: |
Wiley-Blackwell
Feb2007
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| Online Access: | View this record in EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106187306&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106187306 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 10453873 GSB jtl: Journal of Cardiovascular Electrophysiology issn: 10453873 maglogo: Y pubinfo: dt: Feb2007 vid: 18 iid: 2 pid: 480 pub: Wiley-Blackwell place: Malden, Massachusetts artinfo: ui: 106187306 2009512394 10.1111/j.1540-8167.2006.00671.x NLM17338767 106187306 ppf: 185 ppct: 7 formats: fmt: @attributes: type: P tig: atl: Acute evaluation of programmer-guided AV/PV and VV delay optimization comparing an IEGM method and echocardiogram for cardiac resynchronization therapy in heart failure patients and dual-chamber ICD implants. aug: au: Baker JH II McKenzie J III Beau S Greer GS Porterfield J Fedor M Greenberg S Daoud EG Corbisiero R Bailey JR Porterfield L affil: St. Thomas Hospital, Nashville, Tennessee sug: subj: Cardiac Output, Decreased Therapy Cardiac Output, Decreased Ultrasonography Defibrillators, Implantable Echocardiography Methods Outcomes (Health Care) Methods Pacemaker, Artificial Methods Cardiac Resynchronization Therapy Aged Clinical Trials Comparative Studies Electrocardiography Female Funding Source Male Middle Age Multicenter Studies Treatment Outcomes Human Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Introduction: Intracardiac delay optimization of biventricular and dual-chamber pacing devices currently relies on time-consuming echocardiographic measurements. A novel intracardiac electrogram (IEGM) method for atrioventricular (AV/PV) and interventricular (VV) delay optimization was developed, which can be performed during routine device follow-up. Methods and Results: In this prospective, nonrandomized, multi-center trial, patients previously implanted with St. Jude Medical cardiac resynchronization therapy defibrillator (CRT-D) devices or dual-chamber implantable cardioverter defibrillators (ICDs) underwent standard AV/PV and/or VV delay optimization guided by Doppler echocardiogram measurements of the maximum aortic velocity time integral (aortic VTI). Aortic VTI measurements applying the IEGM method recommended delays were then obtained in all patients. Fifty-eight patients (age: 68 ± 11 years; 81% male; 74% ischemic) and 57 patients (age: 71 ± 10 years; 74% male; 71% ischemic) were enrolled for AV/PV and VV delay evaluation, respectively. An independent core lab determined the maximum aortic VTIs. Data analysis of the AV, PV, and VV delays demonstrated the concordance correlation coefficient (CCC) between the standard method aortic VTI values and the IEGM method aortic VTI values was 97.5%, 96.1%, and 96.6%, respectively. All analyses demonstrated that the CCC > 90% (P < 0.05). Conclusion: The automated programmer-based IEGM method provides a reliable and simpler alternative to standard techniques for the optimization of AV/PV and VV delay settings in patients with CRT-D devices and dual-chamber ICDs. pubtype: Academic Journal doctype: clinical trial research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
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