A high-concentration NaCl solution does not stimulate the human trigeminal nerve at the tip of the tongue.
Conclusion. A 3 M NaCl solution does not stimulate the trigeminal nerve in the human tongue. Objectives. In rats, the trigeminal nerve has been reported to respond when the tongue is stimulated by a solution with an NaCl concentration of 0.4 M or greater. We have attempted to clarify whether or not...
| Publicado en: | Acta Oto-Laryngologica Vol. 127; no. 7; pp. 754 - 760 |
|---|---|
| Autores principales: | , , , , , |
| Formato: | diagnostic images research tables/charts tracings Journal Article |
| Publicado: |
Taylor & Francis Ltd
Jul2007
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106196492&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106196492 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00016489 B6D jtl: Acta Oto-Laryngologica issn: 00016489 maglogo: Y pubinfo: dt: Jul2007 vid: 127 iid: 7 pid: 377 pub: Taylor & Francis Ltd place: Philadelphia, Pennsylvania artinfo: ui: 106196492 2009630317 10.1080/00016480601011451 NLM17573572 106196492 ppf: 754 ppct: 6 formats: fmt: @attributes: type: P tig: atl: A high-concentration NaCl solution does not stimulate the human trigeminal nerve at the tip of the tongue. aug: au: Komiyama A Kobayakawa T Toda H Gotow N Ikeda M Saito S affil: Department of Otolaryngology, Nihon University School of Medicine. Tokyo. sug: subj: Sodium Chloride Pharmacodynamics Tongue Injuries Trigeminal Nerve Drug Effects Aged Descriptive Statistics Female Magnetic Resonance Imaging Male Middle Age T-Tests Touch Evaluation Human Aged: 65+ years Middle Aged: 45-64 years Female Male ab: Conclusion. A 3 M NaCl solution does not stimulate the trigeminal nerve in the human tongue. Objectives. In rats, the trigeminal nerve has been reported to respond when the tongue is stimulated by a solution with an NaCl concentration of 0.4 M or greater. We have attempted to clarify whether or not relatively high concentrations of NaCl stimulate the trigeminal nerves of the human tongue. Materials and methods. We examined four patients whose bilateral chorda tympani nerves were resected during middle ear surgeries. We performed subjective tactile and taste tests. Next, we conducted objective examinations of the subjects' tactile and gustatory functions by magnetoencephalography (MEG). Results. The subjective examination confirmed that all four subjects maintained normal tactile sensory functions in their tongues and that the gustatory sensation at their lingual apexes was totally abolished. Furthermore, the objective examination of the tactile function using MEG indicated that their brain responses to trigeminal nerve stimulations were normal. Further examination using MEG failed to produce brain responses to a 3 M NaCl solution in spite of their normally functioning trigeminal nerves. Therefore, we concluded that a 3 M NaCl solution does not stimulate the trigeminal nerve at the tip of the human tongue. pubtype: Academic Journal doctype: diagnostic images research tables/charts tracings Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|