Clinical trial resources on the internet must be designed to reach underrepresented minorities.

Purpose: Internet-based clinical trial information services are being developed to increase recruitment to studies. However, there are limited data that evaluate their ability to reach elderly and underrepresented minority populations. This study was designed to evaluate the ability of an establishe...

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Bibliographic Details
Published in:Cancer Journal Vol. 12; no. 6; pp. 475 - 482
Main Authors: Wilson JJ, Mick R, Wei SJ, Rustgi AK, Markowitz SD, Hampshire M, Metz JM, Wilson, John J, Mick, Rosemarie, Wei, S Jack, Rustgi, Anil K, Markowitz, Sanford D, Hampshire, Maggie, Metz, James M
Format: research tables/charts Journal Article
Published: Lippincott Williams & Wilkins Nov/Dec2006
Online Access:View this record in EBSCOhost
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      dt: Nov/Dec2006
      vid: 12
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      pub: Lippincott Williams & Wilkins
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        10.1097/00130404-200611000-00007
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        atl: Clinical trial resources on the internet must be designed to reach underrepresented minorities.
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        au:
          Wilson JJ
          Mick R
          Wei SJ
          Rustgi AK
          Markowitz SD
          Hampshire M
          Metz JM
          Wilson, John J
          Mick, Rosemarie
          Wei, S Jack
          Rustgi, Anil K
          Markowitz, Sanford D
          Hampshire, Maggie
          Metz, James M
        affil: Fox Chase Virtua Health Cancer Treatment Center, Voorhies, New Jersey 08043, USA
      sug:
        subj:
          Clinical Trials
          Internet
          Minority Groups
          Research Subject Recruitment
          African Americans
          Female
          Funding Source
          Hispanic Americans
          Male
          Middle Age
          Human
          Middle Aged: 45-64 years
          Female
          Male
      ab: Purpose: Internet-based clinical trial information services are being developed to increase recruitment to studies. However, there are limited data that evaluate their ability to reach elderly and underrepresented minority populations. This study was designed to evaluate the ability of an established clinical trials registry to reach these populations based on expected Internet use.Patients and Methods: This study compares general Internet users to participants who enrolled in an Internet based colorectal cancer clinical trials registry established by OncoLink (www.oncolink.org) and the National Colorectal Cancer Research Alliance. Observed rates of demographic groupings were compared to those established for general Internet users.Results: Two thousand, four hundred and thirty-seven participants from the continental United States used the Internet to register for the database. New England, the Mid-Atlantic region, and the Southeast had the highest relative frequency of participation in the database, whereas the Upper Midwest, California, and the South had the lowest rates. Compared to general Internet users, there was an overrepresentation of women (73% vs. 50%) and participants over 55 years old (27% vs. 14%). However, there was an underrepresentation of minorities (10.3% vs. 22%), particularly African Americans (3.1% vs. 8%) and Hispanics (2.8% vs. 9%).Discussion: The Internet is a growing medium for registry into clinical trials databases. However, even taking into account the selection bias of Internet accessibility, there are still widely disparate demographics between general Internet users and those registering for clinical trials, particularly the underrepresentation of minorities. Internet-based educational and recruitment services for clinical trials must be designed to reach these underrepresented minorities to avoid selection biases in future clinical trials.
      pubtype: Academic Journal
      doctype:
        research
        tables/charts
        Journal Article
      ougenre: Article
    language: English
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