Helicobacter pylori stool antigen test.
Objective: Helicobacter pylori ( H.pylori ) infection is usually acquired in early childhood. Invasive techniques used for diagnosis of H.pylori infection require endoscopic examination which is expensive and inconvenient and may cause complications. The aim of this study was to evaluate the perform...
| Publicado en: | Indian Journal of Pediatrics Vol. 72; no. 8; pp. 675 - 679 |
|---|---|
| Autores principales: | , , , , , , , , , , , , , , , |
| Formato: | research tables/charts Journal Article |
| Publicado: |
Springer Nature
Aug2005
|
| Acceso en línea: | Ver este registro en EBSCOhost |
| fields | @attributes: recordID: 1 pdfLink: plink: https://search.ebscohost.com/login.aspx?direct=true&db=ccm&AN=106206293&site=ehost-live header: @attributes: shortDbName: ccm uiTerm: 106206293 longDbName: CINAHL Complete uiTag: AN controlInfo: bkinfo: dissinfo: jinfo: jid: 00195456 1CQL jtl: Indian Journal of Pediatrics issn: 00195456 maglogo: N pubinfo: dt: Aug2005 vid: 72 iid: 8 pid: 237 pub: Springer Nature place: New York, New York artinfo: ui: 106206293 106206293 NLM16131773 2009185818 10.1007/bf02724076 NLM16131773 106206293 ppf: 675 ppct: 4 formats: tig: atl: Helicobacter pylori stool antigen test. aug: au: Gulcan EM Varol A Kutlu T Cullu F Erkan T Adal E Ulucakli O Erdamar S Gulcan, E Mahir Varol, Aydin Kutlu, Tufan Cullu, Fugen Erkan, Tulay Adal, Erdal Ulucakli, Onder Erdamar, Sibel affil: SSK Bakirkoy Maternity and Children's Training Hospital, Department of Pediatric Gastroenterology, Istanbul, Turkey sug: subj: Antigens, Bacterial Analysis Feces Microbiology Gastroscopy Helicobacter Infections Diagnosis Helicobacter Pylori Immunology Abdominal Pain Etiology Adolescence Biopsy Breath Tests Child Child, Preschool Comparative Studies Descriptive Statistics Evaluation Research False Negative Results False Positive Results Feces Analysis Female Helicobacter Infections Drug Therapy Immunoenzyme Techniques Male Predictive Value of Tests Recurrence Reliability Sensitivity and Specificity Serology Urease Diagnostic Use Human Adolescent: 13-18 years Child: 6-12 years Child, Preschool: 2-5 years Female Male ab: Objective: Helicobacter pylori ( H.pylori ) infection is usually acquired in early childhood. Invasive techniques used for diagnosis of H.pylori infection require endoscopic examination which is expensive and inconvenient and may cause complications. The aim of this study was to evaluate the performance of a new noninvasive diagnostic method, stool antigen test for H.pylori in untreated children with recurrent abdominal pain.Methods: Eighty children (35 female, 45 male) who have undergone upper gastrointestinal endoscopy due to recurrent abdominal pain were included in the study. The H.pylori stool antigen test (HpSA) is based on a sandwich enzyme immunoassay with antigen detection. HpSA sensitivity, specificity, and positive and negative predictive values were determined with reference to the results of both histology and rapid urease test as a gold standard ( H. pylori status).Results: While 49 of the 80 children (61%) tested were positive for H.pylori according to the results of both histology and rapid urease test, 28 children had negative H.pylori status. Among those 49 children, 48 were found to be positive by HpSA. Of 28 patients with negative H.pylori status, 28 were H.pylori -negative also in the stool test. The sensitivity, specificity, and positive and negative predictive values of HpSA were found to be 98%, 100%, 100%, and 96.5%, respectively.Conclusion: These findings have demonstrated that HpSA as a relatively simple, inexpensive and time saving noninvasive test is a reliable method for detection of H.pylori infections in children. pubtype: Academic Journal doctype: research tables/charts Journal Article ougenre: Article language: English refInfo: holdings: @attributes: islocal: N |
|---|